Abnormal white matter microstructure in children with sensory processing disorders.

Overview of attention for article published in NeuroImage: Clinical, June 2013
Altmetric Badge

About this score

  • In the top 5% of all articles scored by Altmetric
  • One of the highest-scoring articles from this source (#4 of 264)
  • High score compared to articles of the same age (98th percentile)
  • High score compared to articles of the same age and source (85th percentile)

Mentioned by

Readers on

mendeley
46 Mendeley
citeulike
9 CiteULike
Article title
Abnormal white matter microstructure in children with sensory processing disorders.
Published in
NeuroImage: Clinical, June 2013
DOI 10.1016/j.nicl.2013.06.009
Pubmed ID
Authors

Julia P. Owen, Elysa J. Marco, Shivani Desai, Emily Fourie, Julia Harris, Susanna S. Hill, Anne B. Arnett, Pratik Mukherjee

Abstract

Sensory processing disorders (SPD) affect 5-16% of school-aged children and can cause long-term deficits in intellectual and social development. Current theories of SPD implicate primary sensory cortical areas and higher-order multisensory integration (MSI) cortical regions. We investigate the role of white matter microstructural abnormalities in SPD using diffusion tensor imaging (DTI). DTI was acquired in 16 boys, 8-11 years old, with SPD and 24 age-, gender-, handedness- and IQ-matched neurotypical controls. Behavior was characterized using a parent report sensory behavior measure, the Sensory Profile. Fractional anisotropy (FA), mean diffusivity (MD) and radial diffusivity (RD) were calculated. Tract-based spatial statistics were used to detect significant group differences in white matter integrity and to determine if microstructural parameters were significantly correlated with behavioral measures. Significant decreases in FA and increases in MD and RD were found in the SPD cohort compared to controls, primarily involving posterior white matter including the posterior corpus callosum, posterior corona radiata and posterior thalamic radiations. Strong positive correlations were observed between FA of these posterior tracts and auditory, multisensory, and inattention scores (r = 0.51-0.78; p < 0.001) with strong negative correlations between RD and multisensory and inattention scores (r = - 0.61-0.71; p < 0.001). To our knowledge, this is the first study to demonstrate reduced white matter microstructural integrity in children with SPD. We find that the disrupted white matter microstructure predominantly involves posterior cerebral tracts and correlates strongly with atypical unimodal and multisensory integration behavior. These findings suggest abnormal white matter as a biological basis for SPD and may also distinguish SPD from overlapping clinical conditions such as autism and attention deficit hyperactivity disorder.

Twitter Demographics

The data shown below were collected from the profiles of 53 tweeters who shared this article. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this article. Click here to see the article's page on the Mendeley website.

Geographical breakdown

Country Count As %
United Kingdom 2 4%
United States 2 4%
France 2 4%
Japan 1 2%
Germany 1 2%
Chile 1 2%
Australia 1 2%
Mexico 1 2%
Unknown 35 76%

Demographic breakdown

Readers by professional status Count As %
Ph.D. Student 10 22%
Student (Master) 7 15%
Post Doc 7 15%
Student (Bachelor) 6 13%
Student (Postgraduate) 3 7%
Other 13 28%
Readers by discipline Count As %
Psychology 14 30%
Medicine 11 24%
Biological Sciences 9 20%
Social Sciences 5 11%
Education 3 7%
Other 4 9%

Score in context

This article has an Altmetric score of 96.99. This is our high-level measure of the quality and quantity of online attention that this article has received. This score was calculated when the article was last mentioned on 09 April 2015.
All articles
#21,136
of 3,731,357 articles
Articles in NeuroImage: Clinical
#4
of 264 articles
Articles of similar age
#1,022
of 85,677 articles
Articles of similar age in NeuroImage: Clinical
#1
of 7 articles
Altmetric has tracked 3,731,357 articles across all sources so far. Compared to these this article has done particularly well and is in the 99th percentile: it's in the top 5% of all articles ever tracked by Altmetric.
So far Altmetric has tracked 264 articles from this source. They typically receive a little more attention than average, with a mean score of 6.5. This article has done particularly well, scoring higher than 98% of its peers.
Older articles will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this score to the 85,677 tracked articles that were published within six weeks on either side of this one in any source. This article has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this article to 7 articles from the same source and published within six weeks on either side of this one. This article has scored higher than all of them