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Systemic tryptophan and kynurenine catabolite levels relate to severity of rhinovirus-induced asthma exacerbation: a prospective study with a parallel-group design

Overview of attention for article published in Thorax, July 2013
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Mentioned by

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6 X users

Citations

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51 Dimensions

Readers on

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48 Mendeley
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Title
Systemic tryptophan and kynurenine catabolite levels relate to severity of rhinovirus-induced asthma exacerbation: a prospective study with a parallel-group design
Published in
Thorax, July 2013
DOI 10.1136/thoraxjnl-2013-203728
Pubmed ID
Authors

Koenraad F van der Sluijs, Marianne A van de Pol, Wim Kulik, Annemiek Dijkhuis, Barbara S Smids, Hetty W van Eijk, Jos A Karlas, Richard Molenkamp, Katja C Wolthers, Sebastian L Johnston, Jaring S van der Zee, Peter J Sterk, René Lutter, the RESOLVE research team

Abstract

Patients with allergic asthma have exacerbations which are frequently caused by rhinovirus infection. The antiviral tryptophan-catabolising enzyme indoleamine 2,3-dioxygenase (IDO) is induced by interferon-γ and suppressed by Th2 mediators interleukin (IL)-4 and IL-13. We hypothesised that local IDO activity after viral airway infection is lower in patients with allergic asthma than in healthy controls.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Korea, Republic of 1 2%
Netherlands 1 2%
Australia 1 2%
Unknown 45 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 33%
Student > Ph. D. Student 9 19%
Student > Bachelor 5 10%
Student > Master 5 10%
Other 3 6%
Other 5 10%
Unknown 5 10%
Readers by discipline Count As %
Medicine and Dentistry 16 33%
Biochemistry, Genetics and Molecular Biology 6 13%
Agricultural and Biological Sciences 6 13%
Chemistry 5 10%
Immunology and Microbiology 2 4%
Other 4 8%
Unknown 9 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 February 2014.
All research outputs
#14,459,457
of 25,483,400 outputs
Outputs from Thorax
#4,401
of 5,757 outputs
Outputs of similar age
#108,376
of 209,431 outputs
Outputs of similar age from Thorax
#49
of 75 outputs
Altmetric has tracked 25,483,400 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,757 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.7. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 209,431 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.