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Combining Computational Methods for Hit to Lead Optimization in Mycobacterium Tuberculosis Drug Discovery

Overview of attention for article published in Pharmaceutical Research, October 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

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1 blog
twitter
1 X user

Readers on

mendeley
75 Mendeley
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Title
Combining Computational Methods for Hit to Lead Optimization in Mycobacterium Tuberculosis Drug Discovery
Published in
Pharmaceutical Research, October 2013
DOI 10.1007/s11095-013-1172-7
Pubmed ID
Authors

Sean Ekins, Joel S. Freundlich, Judith V. Hobrath, E. Lucile White, Robert C. Reynolds

Abstract

Tuberculosis treatments need to be shorter and overcome drug resistance. Our previous large scale phenotypic high-throughput screening against Mycobacterium tuberculosis (Mtb) has identified 737 active compounds and thousands that are inactive. We have used this data for building computational models as an approach to minimize the number of compounds tested.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 2 3%
Indonesia 1 1%
United States 1 1%
Italy 1 1%
Unknown 70 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 17%
Researcher 12 16%
Student > Master 10 13%
Student > Bachelor 5 7%
Student > Doctoral Student 4 5%
Other 13 17%
Unknown 18 24%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 15%
Pharmacology, Toxicology and Pharmaceutical Science 11 15%
Chemistry 9 12%
Agricultural and Biological Sciences 6 8%
Medicine and Dentistry 4 5%
Other 13 17%
Unknown 21 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 February 2020.
All research outputs
#3,925,789
of 22,727,570 outputs
Outputs from Pharmaceutical Research
#395
of 2,852 outputs
Outputs of similar age
#37,039
of 211,883 outputs
Outputs of similar age from Pharmaceutical Research
#3
of 32 outputs
Altmetric has tracked 22,727,570 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,852 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 211,883 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.