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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Perinatal programming of adult hippocampal structure and function; emerging roles of stress, nutrition and epigenetics
|
|---|---|
| Published in |
Trends in Neurosciences, August 2013
|
| DOI | 10.1016/j.tins.2013.08.002 |
| Pubmed ID | |
| Authors |
Paul J. Lucassen, Eva F.G. Naninck, Johannes B. van Goudoever, Carlos Fitzsimons, Marian Joels, Aniko Korosi |
| Abstract |
Early-life stress lastingly affects adult cognition and increases vulnerability to psychopathology, but the underlying mechanisms remain elusive. In this Opinion article, we propose that early nutritional input together with stress hormones and sensory stimuli from the mother during the perinatal period act synergistically to program the adult brain, possibly via epigenetic mechanisms. We hypothesize that stress during gestation or lactation affects the intake of macro- and micronutrients, including dietary methyl donors, and/or impairs the dam's metabolism, thereby altering nutrient composition and intake by the offspring. In turn, this may persistently modulate gene expression via epigenetic programming, thus altering hippocampal structure and cognition. Understanding how the combination of stress, nutrition, and epigenetics shapes the adult brain is essential for effective therapies. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 387 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 2% |
| United Kingdom | 3 | <1% |
| Korea, Republic of | 2 | <1% |
| Portugal | 2 | <1% |
| Canada | 2 | <1% |
| Brazil | 1 | <1% |
| South Africa | 1 | <1% |
| Chile | 1 | <1% |
| France | 1 | <1% |
| Other | 6 | 2% |
| Unknown | 362 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 73 | 19% |
| Student > Master | 67 | 17% |
| Student > Bachelor | 56 | 14% |
| Researcher | 47 | 12% |
| Professor | 23 | 6% |
| Other | 70 | 18% |
| Unknown | 51 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 104 | 27% |
| Neuroscience | 74 | 19% |
| Medicine and Dentistry | 43 | 11% |
| Psychology | 41 | 11% |
| Biochemistry, Genetics and Molecular Biology | 19 | 5% |
| Other | 42 | 11% |
| Unknown | 64 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 July 2017.
All research outputs
#19,944,091
of 25,373,627 outputs
Outputs from Trends in Neurosciences
#2,274
of 2,484 outputs
Outputs of similar age
#154,027
of 211,836 outputs
Outputs of similar age from Trends in Neurosciences
#13
of 16 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,484 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.0. This one is in the 7th percentile – i.e., 7% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 211,836 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.