General and specific effects of early-life psychosocial adversities on adolescent grey matter volume

Overview of attention for article published in NeuroImage: Clinical
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  • In the top 5% of all articles scored by Altmetric
  • One of the highest-scoring articles from this source (#3 of 249)
  • High score compared to articles of the same age (98th percentile)
  • High score compared to articles of the same age and source (95th percentile)

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mendeley
17 Mendeley
Article title
General and specific effects of early-life psychosocial adversities on adolescent grey matter volume
Published in
NeuroImage: Clinical
DOI 10.1016/j.nicl.2014.01.001
Pubmed ID
Abstract

Exposure to childhood adversities (CA) is associated with subsequent alterations in regional brain grey matter volume (GMV). Prior studies have focused mainly on severe neglect and maltreatment. The aim of this study was to determine in currently healthy adolescents if exposure to more common forms of CA results in reduced GMV. Effects on brain structure were investigated using voxel-based morphometry in a cross-sectional study of youth recruited from a population-based longitudinal cohort. 58 participants (mean age = 18.4) with (n = 27) or without (n = 31) CA exposure measured retrospectively from maternal interview were included in the study. Measures of recent negative life events (RNLE) recorded at 14 and 17 years, current depressive symptoms, gender, participant/parental psychiatric history, current family functioning perception and 5-HTTLPR genotype were covariates in analyses. A multivariate analysis of adversities demonstrated a general association with a widespread distributed neural network consisting of cortical midline, lateral frontal, temporal, limbic, and cerebellar regions. Univariate analyses showed more specific associations between adversity measures and regional GMV: CA specifically demonstrated reduced vermis GMV and past psychiatric history with reduced medial temporal lobe volume. In contrast RNLE aged 14 was associated with increased lateral cerebellar and anterior cingulate GMV. We conclude that exposure to moderate levels of childhood adversities occurring during childhood and early adolescence exerts effects on the developing adolescent brain. Reducing exposure to adverse social environments during early life may optimize typical brain development and reduce subsequent mental health risks in adult life.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this article. Click here to see the article's page on the Mendeley website.

Geographical breakdown

Country Count As %
United Kingdom 1 6%
Unknown 16 94%

Demographic breakdown

Readers by professional status Count As %
Ph.D. Student 7 41%
Post Doc 4 24%
Student (Master) 2 12%
Senior Lecturer 1 6%
Student (Postgraduate) 1 6%
Other 2 12%
Readers by discipline Count As %
Psychology 12 71%
Social Sciences 2 12%
Physics 1 6%
Biological Sciences 1 6%
Medicine 1 6%
Other 0 0%

Score in context

This article has an Altmetric score of 104.09. This is our high-level measure of the quality and quantity of online attention that this article has received. This score was calculated when the article was last mentioned on 13 August 2014.
All articles
#18,201
of 3,637,659 articles
Articles in NeuroImage: Clinical
#3
of 249 articles
Articles of similar age
#1,175
of 110,883 articles
Articles of similar age in NeuroImage: Clinical
#1
of 22 articles
Altmetric has tracked 3,637,659 articles across all sources so far. Compared to these this article has done particularly well and is in the 99th percentile: it's in the top 5% of all articles ever tracked by Altmetric.
So far Altmetric has tracked 249 articles from this source. They typically receive a little more attention than average, with a mean score of 6.6. This article has done particularly well, scoring higher than 98% of its peers.
Older articles will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this score to the 110,883 tracked articles that were published within six weeks on either side of this one in any source. This article has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this article to 22 articles from the same source and published within six weeks on either side of this one. This article has done particularly well, scoring higher than 95% of its contemporaries.