Title |
Limited geographic distribution of the novel cyclovirus CyCV-VN
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Published in |
Scientific Reports, February 2014
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DOI | 10.1038/srep03967 |
Pubmed ID | |
Authors |
Le Van Tan, Menno D. de Jong, Nguyen Van Kinh, Nguyen Vu Trung, Walter Taylor, Heiman F. L. Wertheim, Arie van der Ende, Lia van der Hoek, Marta Canuti, Martin Crusat, Soeng Sona, Nguyen Hanh Uyen, Abhishek Giri, Nguyen Thi Thuy Chinh BKrong, Ho Dang Trung Nghia, Jeremy Farrar, Juliet E. Bryant, Tran Tinh Hien, Nguyen Van Vinh Chau, H. Rogier van Doorn |
Abstract |
A novel cyclovirus, CyCV-VN, was recently identified in cerebrospinal fluid (CSF) from patients with central nervous system (CNS) infections in central and southern Vietnam. To explore the geographic distribution of this novel virus, more than 600 CSF specimens from patients with suspected CNS infections in northern Vietnam, Cambodia, Nepal and The Netherlands were screened for the presence of CyCV-VN but all were negative. Sequence comparison and phylogenetic analysis between CyCV-VN and another novel cyclovirus recently identified in CSF from Malawian patients indicated that these represent distinct cycloviral species, albeit phylogenetically closely related. The data suggest that CyCV-VN has a limited geographic distribution within southern and central Vietnam. Further research is needed to determine the global distribution and diversity of cycloviruses and importantly their possible association with human disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Netherlands | 1 | 3% |
United States | 1 | 3% |
Unknown | 29 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 5 | 16% |
Researcher | 5 | 16% |
Student > Master | 4 | 13% |
Student > Bachelor | 3 | 10% |
Professor | 2 | 6% |
Other | 7 | 23% |
Unknown | 5 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 29% |
Biochemistry, Genetics and Molecular Biology | 3 | 10% |
Veterinary Science and Veterinary Medicine | 2 | 6% |
Agricultural and Biological Sciences | 2 | 6% |
Computer Science | 2 | 6% |
Other | 4 | 13% |
Unknown | 9 | 29% |