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Superefficient enzymes

Overview of attention for article published in Cellular and Molecular Life Sciences, September 2001
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

Mentioned by

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1 patent
facebook
1 Facebook page
wikipedia
11 Wikipedia pages

Readers on

mendeley
68 Mendeley
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Title
Superefficient enzymes
Published in
Cellular and Molecular Life Sciences, September 2001
DOI 10.1007/pl00000788
Pubmed ID
Authors

M.E. Stroppolo, M. Falconi, A.M. Caccuri, A. Desideri

Abstract

Diffusion-controlled enzymes are characterized by second-order rate constants in the range 10(8)-10(10) M(-1)s(-1). These values are at the upper end of the observed rates of many enzyme-substrate reactions and have been predicted by theoretical studies on bimolecular reaction in solution. Such enzymes are considered to be perfect, since their rate-limiting step is not due to any chemical event but to the diffusional association rate between the enzyme and the substrate. Often the enzyme-substrate encounter is facilitated either through the presence of a strong attractive electric field, produced by charges on the enzyme surface, or through the reduction in the dimension of the search process. Here we provide a brief review of some of the enzymes characterized by a very fast second-order constant, focusing attention on triose phosphate isomerase and Cu,Zn superoxide dismutase taken as typical examples of such highly tuned enzymes.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
France 1 1%
United Kingdom 1 1%
Ireland 1 1%
Mexico 1 1%
Canada 1 1%
Unknown 61 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 19%
Student > Master 12 18%
Student > Ph. D. Student 12 18%
Student > Bachelor 9 13%
Student > Doctoral Student 5 7%
Other 10 15%
Unknown 7 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 29%
Biochemistry, Genetics and Molecular Biology 12 18%
Chemistry 10 15%
Chemical Engineering 4 6%
Medicine and Dentistry 4 6%
Other 7 10%
Unknown 11 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 May 2023.
All research outputs
#5,339,559
of 25,374,917 outputs
Outputs from Cellular and Molecular Life Sciences
#1,151
of 5,877 outputs
Outputs of similar age
#7,049
of 40,836 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#8
of 18 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 78th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,877 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 40,836 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.