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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Amplified Vibrational Circular Dichroism as a Probe of Local Biomolecular Structure
|
|---|---|
| Published in |
Journal of the American Chemical Society, February 2014
|
| DOI | 10.1021/ja411405s |
| Pubmed ID | |
| Authors |
Sérgio R. Domingos, Adriana Huerta-Viga, Lambert Baij, Saeed Amirjalayer, Dorien A. E. Dunnebier, Annemarie J. C. Walters, Markus Finger, Laurence A. Nafie, Bas de Bruin, Wybren Jan Buma, Sander Woutersen |
| Abstract |
We show that the VCD signal intensities of amino acids and oligopeptides can be enhanced by up to 2 orders of magnitude by coupling them to a paramagnetic metal ion. If the redox state of the metal ion is changed from paramagnetic to diamagnetic the VCD amplification vanishes completely. From this observation and from complementary quantum-chemical calculations we conclude that the observed VCD amplification finds its origin in vibronic coupling with low-lying electronic states. We find that the enhancement factor is strongly mode dependent and that it is determined by the distance between the oscillator and the paramagnetic metal ion. This localized character of the VCD amplification provides a unique tool to specifically probe the local structure surrounding a paramagnetic ion and to zoom in on such local structure within larger biomolecular systems. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 1% |
| Switzerland | 1 | 1% |
| Netherlands | 1 | 1% |
| India | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 62 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 20 | 30% |
| Student > Ph. D. Student | 15 | 22% |
| Professor > Associate Professor | 6 | 9% |
| Student > Doctoral Student | 5 | 7% |
| Student > Bachelor | 4 | 6% |
| Other | 11 | 16% |
| Unknown | 6 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 49 | 73% |
| Physics and Astronomy | 5 | 7% |
| Agricultural and Biological Sciences | 2 | 3% |
| Biochemistry, Genetics and Molecular Biology | 1 | 1% |
| Computer Science | 1 | 1% |
| Other | 0 | 0% |
| Unknown | 9 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 March 2014.
All research outputs
#20,223,099
of 22,747,498 outputs
Outputs from Journal of the American Chemical Society
#60,044
of 61,889 outputs
Outputs of similar age
#193,067
of 224,443 outputs
Outputs of similar age from Journal of the American Chemical Society
#492
of 542 outputs
Altmetric has tracked 22,747,498 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 61,889 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 224,443 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 542 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.