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Blood lead, cadmium and mercury in relation to homocysteine and C-reactive protein in women of reproductive age: a panel study

Overview of attention for article published in Environmental Health, August 2017
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Title
Blood lead, cadmium and mercury in relation to homocysteine and C-reactive protein in women of reproductive age: a panel study
Published in
Environmental Health, August 2017
DOI 10.1186/s12940-017-0293-6
Pubmed ID
Authors

Anna Z. Pollack, Sunni L. Mumford, Lindsey Sjaarda, Neil J. Perkins, Farah Malik, Jean Wactawski-Wende, Enrique F. Schisterman

Abstract

To examine the relationship between cadmium, lead, and mercury concentrations with high-sensitivity C-reactive protein (hs-CRP) and homocysteine in women. Metals were measured at enrollment in whole blood. Homocysteine and hs-CRP were measured in one (N = 9) or two (N = 250) menstrual cycles up to 3 and 8 times per cycle, respectively. Linear mixed models with inverse probability of exposure weights to account for time varying confounding were used and models were stratified by dietary and serum vitamin status (dietary: vitamin B6, B12, folate; serum: folate). Geometric mean (95% confidence interval (CI)) concentrations for cadmium, lead, and mercury were 0.29 (0.26-0.31) μg/L, 0.91 (0.86-0.96) μg/dL, and 1.05 (0.93-1.18) μg/L, respectively. Lead was associated with increased homocysteine (0.08; 95% CI: 0.01, 0.15) and this persisted among those in the lower three quartiles of consumption of vitamin B6, B12, folate, and serum folate but was not significant among those in the upper quartile. No associations were observed between metals and hs-CRP. Blood lead was associated with increased homocysteine in a cohort of healthy, premenopausal women but these associations did not persist among those consuming ≥75th percentile of essential micronutrients. Cadmium, lead, and mercury were not associated with hs-CRP concentrations.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 18%
Student > Doctoral Student 5 15%
Student > Master 5 15%
Student > Bachelor 2 6%
Student > Postgraduate 2 6%
Other 4 12%
Unknown 9 27%
Readers by discipline Count As %
Medicine and Dentistry 7 21%
Nursing and Health Professions 3 9%
Biochemistry, Genetics and Molecular Biology 2 6%
Chemistry 2 6%
Agricultural and Biological Sciences 2 6%
Other 7 21%
Unknown 10 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 October 2017.
All research outputs
#14,881,201
of 25,813,008 outputs
Outputs from Environmental Health
#1,078
of 1,619 outputs
Outputs of similar age
#161,196
of 328,753 outputs
Outputs of similar age from Environmental Health
#23
of 30 outputs
Altmetric has tracked 25,813,008 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,619 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 38.0. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,753 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.