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Mendeley readers
Attention Score in Context
| Title |
Role of blood–brain barrier in temporal lobe epilepsy and pharmacoresistance
|
|---|---|
| Published in |
Neuroscience, July 2014
|
| DOI | 10.1016/j.neuroscience.2014.07.030 |
| Pubmed ID | |
| Authors |
E.A. van Vliet, E. Aronica, J.A. Gorter |
| Abstract |
Temporal lobe epilepsy (TLE) is the most common form of focal epilepsies in adults. It is often initiated by an insult or brain injury which triggers a series of alterations which ultimately lead to seizures (epilepsy). In 50-70% of people with TLE the condition cannot be adequately treated by the present antiepileptic drugs. During the last decade the blood-brain barrier (BBB) has received renewed interest as a potential target to treat TLE or its progression. BBB changes have been observed in brain tissue of people with epilepsy as well as in experimental models at the structural, cellular and molecular level that could explain its role in the development and progression of epilepsy (epileptogenesis) as well as the development of drug resistance. Here, we will discuss the role of the BBB in TLE and drug resistance and summarize potential new therapies that may restore normal BBB function in order to put a brake on epileptogenesis and/or to improve drug treatment. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 149 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Finland | 1 | <1% |
| Romania | 1 | <1% |
| Unknown | 147 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 33 | 22% |
| Student > Bachelor | 22 | 15% |
| Researcher | 21 | 14% |
| Student > Master | 18 | 12% |
| Student > Doctoral Student | 7 | 5% |
| Other | 22 | 15% |
| Unknown | 26 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 38 | 26% |
| Neuroscience | 30 | 20% |
| Agricultural and Biological Sciences | 22 | 15% |
| Biochemistry, Genetics and Molecular Biology | 10 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 3% |
| Other | 13 | 9% |
| Unknown | 31 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 August 2020.
All research outputs
#7,960,052
of 25,374,647 outputs
Outputs from Neuroscience
#2,393
of 7,821 outputs
Outputs of similar age
#71,131
of 239,927 outputs
Outputs of similar age from Neuroscience
#24
of 91 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 7,821 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 239,927 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 91 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.