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Genetic variants in candidate genes influencing NAFLD progression

Overview of attention for article published in Journal of Molecular Medicine, September 2011
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1 patent

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41 Mendeley
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Title
Genetic variants in candidate genes influencing NAFLD progression
Published in
Journal of Molecular Medicine, September 2011
DOI 10.1007/s00109-011-0803-x
Pubmed ID
Authors

Michelino Di Rosa, Lucia Malaguarnera

Abstract

Nonalcoholic fatty liver disease (NAFLD) is a metabolic disorder including simple steatosis and nonalcoholic steatohepatitis (NASH). Advanced stages of NASH result ultimately in fibrosis, cirrhosis, and hepatocarcinoma. A diagnosis of NASH entails an increased risk of both liver-related and cardiovascular mortality as worsening of the metabolic syndrome. Because of its escalation, many investigations have been performed to elucidate the pathophysiologic origins of the disease progression. Human epidemiologic studies describing polymorphisms in a number of genes involved in metabolic dysfunctions have contributed to clarify the causes leading to the disease evolution. In this review, we attempt to outline critically the most recently identified genetic variants in NAFLD patients to identify possible risk factors promoting the progression of the disease. The evaluation of altered genotypes together with other clinical variables may facilitate the clinical management of these patients.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Unknown 40 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 12%
Student > Ph. D. Student 5 12%
Student > Doctoral Student 4 10%
Researcher 4 10%
Other 3 7%
Other 5 12%
Unknown 15 37%
Readers by discipline Count As %
Medicine and Dentistry 9 22%
Agricultural and Biological Sciences 8 20%
Biochemistry, Genetics and Molecular Biology 2 5%
Sports and Recreations 2 5%
Physics and Astronomy 1 2%
Other 2 5%
Unknown 17 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 March 2022.
All research outputs
#7,711,992
of 23,452,723 outputs
Outputs from Journal of Molecular Medicine
#522
of 1,569 outputs
Outputs of similar age
#44,432
of 127,029 outputs
Outputs of similar age from Journal of Molecular Medicine
#5
of 13 outputs
Altmetric has tracked 23,452,723 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,569 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 127,029 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.