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The labyrinth of autoinflammatory disorders: a snapshot on the activity of a third-level center in Italy

Overview of attention for article published in Clinical Rheumatology, June 2014
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Title
The labyrinth of autoinflammatory disorders: a snapshot on the activity of a third-level center in Italy
Published in
Clinical Rheumatology, June 2014
DOI 10.1007/s10067-014-2721-0
Pubmed ID
Authors

Luca Cantarini, Antonio Vitale, Orso Maria Lucherini, Caterina De Clemente, Francesco Caso, Luisa Costa, Giacomo Emmi, Elena Silvestri, Flora Magnotti, Maria Cristina Maggio, Eugenia Prinzi, Giuseppe Lopalco, Bruno Frediani, Rolando Cimaz, Mauro Galeazzi, Donato Rigante

Abstract

Autoinflammatory disorders (AIDs) are a novel class of diseases elicited by mutations in genes regulating the homeostasis of innate immune complexes, named inflammasomes, which lead to uncontrolled oversecretion of the proinflammatory cytokine interleukin-1β. Protean inflammatory symptoms are variably associated with periodic fever, depicting multiple specific conditions. Childhood is usually the lifetime in which most hereditary AIDs start, though still a relevant number of patients may experience a delayed disease onset and receive a definite diagnosis during adulthood. As a major referral laboratory for patients with recurrent fevers, we have tested samples from 787 patients in the period September 2007-March 2014, with a total of 1,328 AID-related genes evaluated and a gene/patient ratio of 1.69. In this report, we describe our experience in the clinical approach to AIDs, highlight the most striking differences between child and adult-onset AIDs, and shed an eye-opening insight into their diagnostic process.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 25%
Other 4 14%
Lecturer 3 11%
Professor > Associate Professor 3 11%
Researcher 3 11%
Other 3 11%
Unknown 5 18%
Readers by discipline Count As %
Medicine and Dentistry 13 46%
Immunology and Microbiology 3 11%
Biochemistry, Genetics and Molecular Biology 1 4%
Business, Management and Accounting 1 4%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Other 3 11%
Unknown 6 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 September 2015.
All research outputs
#20,233,547
of 22,759,618 outputs
Outputs from Clinical Rheumatology
#2,616
of 2,990 outputs
Outputs of similar age
#192,651
of 228,102 outputs
Outputs of similar age from Clinical Rheumatology
#40
of 45 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,990 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.