Title |
Patient-Based Transcriptome-Wide Analysis Identify Interferon and Ubiquination Pathways as Potential Predictors of Influenza A Disease Severity
|
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Published in |
PLOS ONE, November 2014
|
DOI | 10.1371/journal.pone.0111640 |
Pubmed ID | |
Authors |
Long Truong Hoang, Thomas Tolfvenstam, Eng Eong Ooi, Chiea Chuen Khor, Ahmand Nazri Mohamed Naim, Eliza Xin Pei Ho, Swee Hoe Ong, Heiman F. Wertheim, Annette Fox, Chau Van Vinh Nguyen, Ngoc My Nghiem, Tuan Manh Ha, Anh Thi Ngoc Tran, Paul Tambayah, Raymond Lin, Chariya Sangsajja, Weerawat Manosuthi, Chareon Chuchottaworn, Piamlarp Sansayunh, Tawee Chotpitayasunondh, Piyarat Suntarattiwong, Kulkanya Chokephaibulkit, Pilaipan Puthavathana, Menno D. de Jong, Jeremy Farrar, H. Rogier van Doorn, Martin Lloyd Hibberd |
Abstract |
The influenza A virus is an RNA virus that is responsible for seasonal epidemics worldwide with up to five million cases of severe illness and 500,000 deaths annually according to the World Health Organization estimates. The factors associated with severe diseases are not well defined, but more severe disease is more often seen among persons aged >65 years, infants, pregnant women, and individuals of any age with underlying health conditions. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 5% |
Netherlands | 1 | 2% |
Unknown | 38 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 22% |
Student > Bachelor | 8 | 20% |
Student > Ph. D. Student | 6 | 15% |
Student > Doctoral Student | 3 | 7% |
Professor > Associate Professor | 3 | 7% |
Other | 3 | 7% |
Unknown | 9 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 27% |
Agricultural and Biological Sciences | 10 | 24% |
Immunology and Microbiology | 5 | 12% |
Biochemistry, Genetics and Molecular Biology | 3 | 7% |
Veterinary Science and Veterinary Medicine | 1 | 2% |
Other | 2 | 5% |
Unknown | 9 | 22% |