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Iodine-Containing Mass-Defect-Tuned Dendrimers for Use as Internal Mass Spectrometry Calibrants

Overview of attention for article published in Journal of the American Society for Mass Spectrometry, December 2017
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Title
Iodine-Containing Mass-Defect-Tuned Dendrimers for Use as Internal Mass Spectrometry Calibrants
Published in
Journal of the American Society for Mass Spectrometry, December 2017
DOI 10.1007/s13361-017-1849-y
Pubmed ID
Authors

Joseph A. Giesen, Benjamin J. Diament, Scott M. Grayson

Abstract

Calibrants based on synthetic dendrimers have been recently proposed as a versatile alternative to peptides and proteins for both MALDI and ESI mass spectrometry calibration. Because of their modular synthetic platform, dendrimer calibrants are particularly amenable to tailoring for specific applications. Utilizing this versatility, a set of dendrimers has been designed as an internal calibrant with a tailored mass defect to differentiate them from the majority of natural peptide analytes. This was achieved by incorporating a tris-iodinated aromatic core as an initiator for the dendrimer synthesis, thereby affording multiple calibration points (m/z range 600-2300) with an optimized mass-defect offset relative to all peptides composed of the 20 most common proteinogenic amino acids. Graphical abstract ᅟ.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 33%
Researcher 1 11%
Lecturer 1 11%
Student > Doctoral Student 1 11%
Unknown 3 33%
Readers by discipline Count As %
Chemistry 4 44%
Veterinary Science and Veterinary Medicine 1 11%
Unknown 4 44%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 December 2017.
All research outputs
#20,663,600
of 25,382,440 outputs
Outputs from Journal of the American Society for Mass Spectrometry
#3,086
of 3,835 outputs
Outputs of similar age
#341,202
of 447,047 outputs
Outputs of similar age from Journal of the American Society for Mass Spectrometry
#37
of 49 outputs
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So far Altmetric has tracked 3,835 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
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We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.