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Hemodynamic response to coupled plasmafiltration-adsorption in human septic shock

Overview of attention for article published in Intensive Care Medicine, March 2003
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

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48 Mendeley
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Title
Hemodynamic response to coupled plasmafiltration-adsorption in human septic shock
Published in
Intensive Care Medicine, March 2003
DOI 10.1007/s00134-003-1724-0
Pubmed ID
Authors

Marco Formica, Carlo Olivieri, Sergio Livigni, Giulio Cesano, Antonella Vallero, Mariella Maio, Ciro Tetta

Abstract

The objective was to examine the effect of repeated applications of coupled plasmafiltration-adsorption on the hemodynamic response in septic shock patients hospitalized in intensive care units (ICUs). Prospective, intention-to-treat. General ICU of a tertiary care, non-teaching, 400-bed, city hospital. Twelve consecutive mechanically ventilated septic shock patients, with or without concomitant acute renal failure (ARF). A median of 10 consecutive sessions (prescribed treatment time: 10 h/session; delivered duration: 8.43+/-1.37 h/min) of coupled plasmafiltration-adsorption for each patient. Mean arterial pressure (77.2+/-12.5 [CI 95%; 74.5-79.8] vs. 83.3+/-14.1 [CI 95%; 80.3-86.3] mm Hg; [ p<0.001]), cardiac index (4.03+/-0.89 [CI 95%; 3.83-4.22] vs. 3.46+/-0.82 [CI 95%; 3.28-3.64] L/m(2)/min; [ p<0.001]), systemic vascular resistance index (1,388+/-496 [CI 95%; 1,278-1,497] vs. 1,753+/-516 [CI 95%; 1,639-1,867] dynes x s/cm(5); [ p<0.001]), PO2/FIO2 ratio (204+/-87 [CI 95%; 185-223] vs. 238+/-82 [CI 95%; 220-256]; [ p<0.001]), significantly improved during 100 global treatments (pre- vs. post-treatment values). Intra-thoracic blood volume and extra-vascular lung water did not change across treatments. Vasopressor requirement was reduced: norepinephrine decrease from an infusion rate of 0.13+/-0.07 (CI 95%; 0.06-0.16) to 0 gamma/kg/min after a mean of 5.3+/-2.7 sessions. C reactive protein (CRP) significantly decreased (from 29.3+/-7.3 vs. 7.9+/-4.8; p<0.0001) during treatment. Survival was 90% at day 28 and 70% at day 90. Coupled plasmafiltration-adsorption was a feasible and safe extracorporeal treatment and exerted a remarkable improvement in the hemodynamics, the pulmonary function, and the outcome in septic shock patients with or without concomitant ARF.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 3 6%
Italy 2 4%
Unknown 43 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 23%
Student > Postgraduate 6 13%
Professor > Associate Professor 6 13%
Other 4 8%
Student > Bachelor 3 6%
Other 8 17%
Unknown 10 21%
Readers by discipline Count As %
Medicine and Dentistry 27 56%
Biochemistry, Genetics and Molecular Biology 2 4%
Chemical Engineering 2 4%
Nursing and Health Professions 2 4%
Agricultural and Biological Sciences 2 4%
Other 3 6%
Unknown 10 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2011.
All research outputs
#6,712,190
of 25,374,647 outputs
Outputs from Intensive Care Medicine
#2,829
of 5,410 outputs
Outputs of similar age
#18,184
of 62,955 outputs
Outputs of similar age from Intensive Care Medicine
#10
of 22 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 5,410 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 29.6. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 62,955 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.