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Exposure to hazardous air pollutants and risk of incident breast cancer in the Nurses’ Health Study II

Overview of attention for article published in Environmental Health, March 2018
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  • Good Attention Score compared to outputs of the same age (67th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (58th percentile)

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Title
Exposure to hazardous air pollutants and risk of incident breast cancer in the Nurses’ Health Study II
Published in
Environmental Health, March 2018
DOI 10.1186/s12940-018-0372-3
Pubmed ID
Authors

Jaime E. Hart, Kimberly A. Bertrand, Natalie DuPre, Peter James, Verónica M. Vieira, Trang VoPham, Maggie R. Mittleman, Rulla M. Tamimi, Francine Laden

Abstract

Findings from a recent prospective cohort study in California suggested increased risk of breast cancer associated with higher exposure to certain carcinogenic and estrogen-disrupting hazardous air pollutants (HAPs). However, to date, no nationwide studies have evaluated these possible associations. Our objective was to examine the impacts of mammary carcinogen and estrogen disrupting HAPs on risk of invasive breast cancer in a nationwide cohort. We assigned HAPs from the US Environmental Protection Agency's 2002 National Air Toxics Assessment to 109,239 members of the nationwide, prospective Nurses' Health Study II (NHSII). Risk of overall invasive, estrogen receptor (ER)-positive (ER+), and ER-negative (ER-) breast cancer with increasing quartiles of exposure were assessed in time-varying multivariable proportional hazards models, adjusted for traditional breast cancer risk factors. A total of 3321 invasive cases occurred (2160 ER+, 558 ER-) during follow-up 1989-2011. Overall, there was no consistent pattern of elevated risk of the HAPs with risk of breast cancer. Suggestive elevations were only seen with increasing 1,2-dibromo-3-chloropropane exposures (multivariable adjusted HR of overall breast cancer = 1.12, 95% CI: 0.98-1.29; ER+ breast cancer HR = 1.09; 95% CI: 0.92, 1.30; ER- breast cancer HR = 1.14; 95% CI: 0.81, 1.61; each in the top exposure quartile compared to the lowest). Exposures to HAPs during adulthood were not consistently associated with an increased risk of overall or estrogen-receptor subtypes of invasive breast cancer in this nationwide cohort of women.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 75 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 12%
Student > Ph. D. Student 6 8%
Student > Bachelor 6 8%
Professor 5 7%
Student > Doctoral Student 5 7%
Other 16 21%
Unknown 28 37%
Readers by discipline Count As %
Medicine and Dentistry 15 20%
Agricultural and Biological Sciences 5 7%
Engineering 5 7%
Chemistry 3 4%
Social Sciences 3 4%
Other 13 17%
Unknown 31 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 October 2022.
All research outputs
#6,221,049
of 23,538,320 outputs
Outputs from Environmental Health
#734
of 1,525 outputs
Outputs of similar age
#107,067
of 331,288 outputs
Outputs of similar age from Environmental Health
#14
of 31 outputs
Altmetric has tracked 23,538,320 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 1,525 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 33.1. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,288 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.