Title |
Genome-wide mapping of human loci for essential hypertension
|
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Published in |
The Lancet, June 2003
|
DOI | 10.1016/s0140-6736(03)13722-1 |
Pubmed ID | |
Authors |
Mark Caulfield, Patricia Munroe, Janine Pembroke, Nilesh Samani, Anna Dominiczak, Morris Brown, John Webster, Peter Ratcliffe, Suzanne O'Shea, Jeanette Papp, Elizabeth Taylor, Richard Dobson, Joanne Knight, Stephen Newhouse, Joel Hooper, Wai Lee, Nick Brain, David Clayton, G Mark Lathrop, Martin Farrall, John Connell, for The MRC British Genetics of Hypertension Study, Nigel Benjamin |
Abstract |
Blood pressure may contribute to 50% of the global cardiovascular disease epidemic. By understanding the genes predisposing to common disorders such as human essential hypertension we may gain insights into novel pathophysiological mechanisms and potential therapeutic targets. In the Medical Research Council BRItish Genetics of HyperTension (BRIGHT) study, we aim to identify these genetic factors by scanning the human genome for susceptibility genes for essential hypertension. We describe the results of a genome scan for hypertension in a large white European population. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 2% |
Mexico | 1 | 2% |
United States | 1 | 2% |
Unknown | 62 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 17% |
Student > Ph. D. Student | 7 | 11% |
Student > Postgraduate | 7 | 11% |
Professor | 7 | 11% |
Student > Master | 7 | 11% |
Other | 18 | 28% |
Unknown | 8 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 32% |
Agricultural and Biological Sciences | 11 | 17% |
Biochemistry, Genetics and Molecular Biology | 10 | 15% |
Computer Science | 2 | 3% |
Veterinary Science and Veterinary Medicine | 1 | 2% |
Other | 7 | 11% |
Unknown | 13 | 20% |