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Mendeley readers
Attention Score in Context
| Title |
Regulated expression patterns of IRX-2, an Iroquois-class homeobox gene, in the human breast
|
|---|---|
| Published in |
Cell and Tissue Research, May 1999
|
| DOI | 10.1007/s004410051316 |
| Pubmed ID | |
| Authors |
Michael T. Lewis, Sarajane Ross, Phyllis A. Strickland, C. John Snyder, C. W. Daniel |
| Abstract |
In the mouse mammary gland, homeobox gene expression patterns suggest roles in development and neoplasia. In the human breast, we now identify a family of Iroquois-class (IRX) homeobox genes. One gene, IRX-2, is expressed in discrete epithelial cell lineages being found in ductal and lobular epithelium, but not in myoepithelium. Expression is absent from associated mesenchymal adipose stroma. During gland development, expression is concentrated in terminal end buds and terminal lobules and is reduced in a subset of epithelial cells during lactation. In contrast to observations for many homeobox genes in the mouse mammary gland in which homeobox gene expression is lost on neoplastic progression, IRX-2 expression is maintained in human mammary neoplasias. Data suggest IRX-2 functions in epithelial cell differentiation and demonstrate regulated expression during ductal and lobular proliferation as well as lactation. |
Mendeley readers
The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 11% |
| Germany | 1 | 5% |
| Unknown | 16 | 84% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 5 | 26% |
| Researcher | 5 | 26% |
| Student > Ph. D. Student | 3 | 16% |
| Student > Postgraduate | 2 | 11% |
| Student > Doctoral Student | 2 | 11% |
| Other | 1 | 5% |
| Unknown | 1 | 5% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 5 | 26% |
| Biochemistry, Genetics and Molecular Biology | 4 | 21% |
| Agricultural and Biological Sciences | 3 | 16% |
| Nursing and Health Professions | 2 | 11% |
| Psychology | 1 | 5% |
| Other | 1 | 5% |
| Unknown | 3 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 September 2021.
All research outputs
#5,611,796
of 26,017,215 outputs
Outputs from Cell and Tissue Research
#297
of 2,321 outputs
Outputs of similar age
#5,907
of 37,768 outputs
Outputs of similar age from Cell and Tissue Research
#3
of 14 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,321 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 37,768 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.