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Integrated preclinical and clinical development of S-trans, trans-farnesylthiosalicylic acid (FTS, Salirasib) in pancreatic cancer

Overview of attention for article published in Investigational New Drugs, May 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (76th percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

Mentioned by

patent
1 patent
wikipedia
1 Wikipedia page

Readers on

mendeley
77 Mendeley
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Title
Integrated preclinical and clinical development of S-trans, trans-farnesylthiosalicylic acid (FTS, Salirasib) in pancreatic cancer
Published in
Investigational New Drugs, May 2012
DOI 10.1007/s10637-012-9818-6
Pubmed ID
Authors

Daniel Laheru, Preeti Shah, N. V. Rajeshkumar, Florencia McAllister, Gretchen Taylor, Howard Goldsweig, Dung T. Le, Ross Donehower, Antonio Jimeno, Sheila Linden, Ming Zhao, Dongweon Song, Michelle A. Rudek, Manuel Hidalgo

Abstract

S-trans,trans-Farnesylthiosalicylic Acid (FTS, salirasib) inhibits Ras-dependent cell growth by dislodging all isoforms of Ras, including mutant Ras, from the plasma membrane. This study evaluated the activity, safety, and toxicity of salirasib in preclinical models and patients with metastatic pancreatic adenocarcinoma (PDA).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 1%
Unknown 76 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 23%
Researcher 13 17%
Student > Bachelor 10 13%
Student > Master 7 9%
Other 5 6%
Other 11 14%
Unknown 13 17%
Readers by discipline Count As %
Medicine and Dentistry 16 21%
Biochemistry, Genetics and Molecular Biology 14 18%
Agricultural and Biological Sciences 14 18%
Chemistry 4 5%
Psychology 3 4%
Other 7 9%
Unknown 19 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 May 2023.
All research outputs
#5,021,171
of 23,862,416 outputs
Outputs from Investigational New Drugs
#176
of 1,221 outputs
Outputs of similar age
#33,331
of 165,882 outputs
Outputs of similar age from Investigational New Drugs
#3
of 14 outputs
Altmetric has tracked 23,862,416 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,221 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 165,882 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.