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Obesity increases the risk of renal involvement in children with Henoch–Schönlein purpura

Overview of attention for article published in European Journal of Pediatrics, April 2015
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Title
Obesity increases the risk of renal involvement in children with Henoch–Schönlein purpura
Published in
European Journal of Pediatrics, April 2015
DOI 10.1007/s00431-015-2547-z
Pubmed ID
Authors

Yong-Li Zhao, Zheng-Juan Liu, Xue-Mei Bai, Yu-Chuan Wang, Guo-Hua Li, Xue-Yan Yan

Abstract

The main aim of this study was to evaluate the relationship between obesity and renal involvement in children with Henoch-Schönlein purpura (HSP). A retrospective study of 141 pediatric patients with HSP was conducted in our hospital. The clinical data of all patients were collected from the electronic medical record management system from January 2010 to June 2014. The possible risk factors of renal involvement, especially obesity, were analyzed using univariate and multivariate analyses. Renal involvement occurred in 45/141 of the patients. A univariate analysis showed that an age more than 7 years at onset, persistent purpura, obesity, time from symptoms onset to diagnosis more than 14 days, and decreased C3 all increased the risk of renal involvement in HSP. The forward stepwise logistic regression analysis indicated obesity (odds ratio (OR) 4.43, 95 % confidence interval (CI) 1.896 to 10.358), age more than 7 years at onset (OR 2.81, 95 % CI 1.142 to 6.907), and persistent purpura (OR 2.57, 95 % CI 1.119 to 5.909) were independent risk factors for renal involvement. Our results show that obesity can increase the hazard of renal involvement in children with HSP and reconfirm that older age at onset and persistent purpura are the independent risk factors for renal involvement. What is Known: • There have been some reports that obesity was associated with the development of renal injury. • It is not clear whether obesity can increase the risk of renal involvement in children with HSP. What is New: • The main finding of this study is that obesity can increase the hazard of renal involvement in children with HSP.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 22%
Researcher 3 13%
Librarian 2 9%
Student > Ph. D. Student 2 9%
Student > Master 2 9%
Other 4 17%
Unknown 5 22%
Readers by discipline Count As %
Medicine and Dentistry 10 43%
Nursing and Health Professions 4 17%
Business, Management and Accounting 1 4%
Social Sciences 1 4%
Immunology and Microbiology 1 4%
Other 0 0%
Unknown 6 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 April 2015.
All research outputs
#20,273,512
of 22,805,349 outputs
Outputs from European Journal of Pediatrics
#3,437
of 3,697 outputs
Outputs of similar age
#224,016
of 265,515 outputs
Outputs of similar age from European Journal of Pediatrics
#55
of 57 outputs
Altmetric has tracked 22,805,349 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,697 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 265,515 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.