Title |
Wanderer, an interactive viewer to explore DNA methylation and gene expression data in human cancer
|
---|---|
Published in |
Epigenetics & Chromatin, June 2015
|
DOI | 10.1186/s13072-015-0014-8 |
Pubmed ID | |
Authors |
Anna Díez-Villanueva, Izaskun Mallona, Miguel A. Peinado |
Abstract |
The Cancer Genome Atlas (TCGA) offers a multilayered view of genomics and epigenomics data of many human cancer types. However, the retrieval of expression and methylation data from TCGA is a cumbersome and time-consuming task. Wanderer is an intuitive Web tool allowing real time access and visualization of gene expression and DNA methylation profiles from TCGA. Given a gene query and selection of a TCGA dataset (e.g., colon adenocarcinomas), the Web resource provides the expression profile, at the single exon level, and the DNA methylation levels of HumanMethylation450 BeadChip loci inside or in the vicinity of the queried gene. Graphic and table outputs include individual and summary data as well as statistical tests, allowing the comparison of tumor and normal profiles and the exploration along the genomic locus and across tumor collections. Wanderer offers a simple interface to straightforward access to TCGA data, amenable to experimentalists and clinicians without bioinformatics expertise. Wanderer may be accessed at http://maplab.cat/wanderer. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 27% |
United Kingdom | 2 | 13% |
Canada | 1 | 7% |
Spain | 1 | 7% |
Venezuela, Bolivarian Republic of | 1 | 7% |
Australia | 1 | 7% |
Unknown | 5 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 10 | 67% |
Scientists | 5 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
United States | 1 | <1% |
Denmark | 1 | <1% |
Unknown | 116 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 32 | 27% |
Researcher | 20 | 17% |
Student > Master | 13 | 11% |
Student > Bachelor | 11 | 9% |
Student > Doctoral Student | 7 | 6% |
Other | 13 | 11% |
Unknown | 23 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 40 | 34% |
Agricultural and Biological Sciences | 25 | 21% |
Medicine and Dentistry | 10 | 8% |
Immunology and Microbiology | 4 | 3% |
Mathematics | 3 | 3% |
Other | 6 | 5% |
Unknown | 31 | 26% |