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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Cannabinoids and Epilepsy
|
|---|---|
| Published in |
Neurotherapeutics, October 2015
|
| DOI | 10.1007/s13311-015-0375-5 |
| Pubmed ID | |
| Authors |
Evan C Rosenberg, Richard W Tsien, Benjamin J Whalley, Orrin Devinsky |
| Abstract |
Cannabis has been used for centuries to treat seizures. Recent anecdotal reports, accumulating animal model data, and mechanistic insights have raised interest in cannabis-based antiepileptic therapies. In this study, we review current understanding of the endocannabinoid system, characterize the pro- and anticonvulsive effects of cannabinoids [e.g., Δ9-tetrahydrocannabinol and cannabidiol (CBD)], and highlight scientific evidence from pre-clinical and clinical trials of cannabinoids in epilepsy. These studies suggest that CBD avoids the psychoactive effects of the endocannabinoid system to provide a well-tolerated, promising therapeutic for the treatment of seizures, while whole-plant cannabis can both contribute to and reduce seizures. Finally, we discuss results from a new multicenter, open-label study using CBD in a population with treatment-resistant epilepsy. In all, we seek to evaluate our current understanding of cannabinoids in epilepsy and guide future basic science and clinical studies. |
X Demographics
The data shown below were collected from the profiles of 38 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 6 | 16% |
| United States | 5 | 13% |
| Mexico | 3 | 8% |
| Canada | 2 | 5% |
| Ireland | 1 | 3% |
| France | 1 | 3% |
| Comoros | 1 | 3% |
| Denmark | 1 | 3% |
| Spain | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 17 | 45% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 31 | 82% |
| Scientists | 3 | 8% |
| Practitioners (doctors, other healthcare professionals) | 3 | 8% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 624 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| Brazil | 1 | <1% |
| Austria | 1 | <1% |
| Puerto Rico | 1 | <1% |
| South Africa | 1 | <1% |
| Unknown | 618 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 101 | 16% |
| Researcher | 84 | 13% |
| Student > Master | 83 | 13% |
| Student > Ph. D. Student | 61 | 10% |
| Other | 45 | 7% |
| Other | 99 | 16% |
| Unknown | 151 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 97 | 16% |
| Agricultural and Biological Sciences | 61 | 10% |
| Neuroscience | 58 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 50 | 8% |
| Biochemistry, Genetics and Molecular Biology | 50 | 8% |
| Other | 129 | 21% |
| Unknown | 179 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 181. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 November 2023.
All research outputs
#226,160
of 25,816,430 outputs
Outputs from Neurotherapeutics
#25
of 1,321 outputs
Outputs of similar age
#2,891
of 287,873 outputs
Outputs of similar age from Neurotherapeutics
#3
of 19 outputs
Altmetric has tracked 25,816,430 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,321 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.7. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 287,873 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.