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Acquired resistance to cancer immunotherapy

Overview of attention for article published in Seminars in Immunopathology, July 2018
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (62nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (58th percentile)

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60 Mendeley
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Title
Acquired resistance to cancer immunotherapy
Published in
Seminars in Immunopathology, July 2018
DOI 10.1007/s00281-018-0692-y
Pubmed ID
Authors

Arianna Draghi, Christopher Aled Chamberlain, Andrew Furness, Marco Donia

Abstract

In recent times, advances in cancer immunotherapy have yielded impressive, durable clinical responses in patients with varied subtypes of cancer. However, a significant proportion of patients who initially demonstrate encouraging tumor regression develop resistance and progress over time. The identification of novel therapeutic approaches to overcome resistance may result in significantly improved clinical outcomes and remains an area of high scientific priority. This review aims to summarize the current knowledge regarding the role of both tumor-intrinsic and tumor-extrinsic factors in the development of resistance to cancer immunotherapy and to discuss current and possible future therapeutic strategies targeting these mechanisms.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 60 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 18%
Student > Master 7 12%
Student > Ph. D. Student 6 10%
Student > Bachelor 5 8%
Student > Postgraduate 4 7%
Other 7 12%
Unknown 20 33%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 18%
Immunology and Microbiology 10 17%
Medicine and Dentistry 8 13%
Agricultural and Biological Sciences 4 7%
Environmental Science 1 2%
Other 4 7%
Unknown 22 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 July 2018.
All research outputs
#7,356,230
of 23,923,788 outputs
Outputs from Seminars in Immunopathology
#206
of 556 outputs
Outputs of similar age
#122,660
of 330,881 outputs
Outputs of similar age from Seminars in Immunopathology
#5
of 12 outputs
Altmetric has tracked 23,923,788 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 556 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,881 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.