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Attention Score in Context
| Title |
Intrinsic brain abnormalities in irritable bowel syndrome and effect of anxiety and depression
|
|---|---|
| Published in |
Brain Imaging and Behavior, November 2015
|
| DOI | 10.1007/s11682-015-9478-1 |
| Pubmed ID | |
| Authors |
Rongfeng Qi, Chang Liu, Jun Ke, Qiang Xu, Jianhui Zhong, Fangyu Wang, Long Jiang Zhang, Guang Ming Lu |
| Abstract |
This resting-state functional magnetic resonance imaging (rs-fMRI) study investigated intrinsic brain abnormalities in irritable bowel syndrome (IBS) and effect of anxiety and depression. Thirty IBS patients and 31 matched healthy controls underwent rs-fMRI scanning. Regional brain activity was evaluated by measuring the amplitude of low-frequency fluctuation (ALFF) and compared between IBS patients and healthy controls with a two-sample t-test. Areas with abnormal ALFF were further used as seeds in subsequent inter-regional functional connectivity (FC) analysis. Statistical analyses were also performed by including anxiety and depression as covariates to evaluate their effect. Compared to healthy controls, IBS patients showed decreased ALFF in several core default mode network regions (medial prefrontal cortex [MPFC], posterior cingulate cortex [PCC], bilateral inferior parietal cortices [IPC]), and in middle frontal cortex, right orbital part of the superior frontal gyrus (ORBsup), dorsal anterior cingulate cortex (dACC), and ventral anterior cingulated cortex (vACC), while they showed increased ALFF in bilateral posterior insula and cuneus. In addition, IBS patients revealed decreased inter-regional positive FC between MPFC and right ORBsup, between vACC and PCC, as well as decreased negative FC between MPFC and left posterior insula, while they showed increased negative FC between MPFC and cuneus. The inclusion of anxiety and depression as covariates abolished ALFF differences in dACC and vACC, but none of the FC differences. IBS patients had disturbed intrinsic brain function. High levels of anxiety and depression in IBS patients could account for their decreased intrinsic brain activity in regions (the ACC) involved in affective processing. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 82 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 11 | 13% |
| Student > Ph. D. Student | 10 | 12% |
| Student > Bachelor | 8 | 10% |
| Student > Doctoral Student | 7 | 9% |
| Researcher | 4 | 5% |
| Other | 12 | 15% |
| Unknown | 30 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 17% |
| Neuroscience | 13 | 16% |
| Psychology | 12 | 15% |
| Agricultural and Biological Sciences | 3 | 4% |
| Nursing and Health Professions | 3 | 4% |
| Other | 4 | 5% |
| Unknown | 33 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 November 2015.
All research outputs
#18,430,119
of 22,832,057 outputs
Outputs from Brain Imaging and Behavior
#863
of 1,155 outputs
Outputs of similar age
#203,078
of 282,783 outputs
Outputs of similar age from Brain Imaging and Behavior
#23
of 31 outputs
Altmetric has tracked 22,832,057 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,155 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 282,783 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.