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Mendeley readers
Attention Score in Context
| Title |
Purine metabolism and the microaerophily of Helicobacter pylori
|
|---|---|
| Published in |
Archives of Microbiology, December 1997
|
| DOI | 10.1007/s002030050521 |
| Pubmed ID | |
| Authors |
G. L. Mendz, Andrew J. Shepley, Stuart L. Hazell, Mark A. Smith |
| Abstract |
The requirements for purine nucleotide synthesis, the effects of purine analogues, and the metabolism of adenine in the bacterium Helicobacter pylori were investigated employing cell culture techniques and one-dimensional NMR spectroscopy. Bacterial cells grew and proliferated in media lacking preformed purines, indicating that H. pylori can synthesize purine nucleotides de novo to meet its requirements. Blocking of this pathway in the absence of sufficient preformed purines for salvage nucleotide synthesis led to cell death. Analogues of purine nucleobases and nucleosides taken up by the cells were cytotoxic, suggesting that salvage routes could be exploited for therapy. Adenine or hypoxanthine were able to substitute for catalase in supporting cell growth and proliferation, suggesting a role for these bases in maintaining the microaerophilic conditions essentially required by the bacterium. |
Mendeley readers
The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 4% |
| Unknown | 24 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 7 | 28% |
| Researcher | 7 | 28% |
| Student > Bachelor | 3 | 12% |
| Student > Master | 2 | 8% |
| Professor | 2 | 8% |
| Other | 0 | 0% |
| Unknown | 4 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 7 | 28% |
| Biochemistry, Genetics and Molecular Biology | 4 | 16% |
| Immunology and Microbiology | 3 | 12% |
| Medicine and Dentistry | 3 | 12% |
| Chemistry | 2 | 8% |
| Other | 0 | 0% |
| Unknown | 6 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 January 2014.
All research outputs
#8,535,684
of 25,374,917 outputs
Outputs from Archives of Microbiology
#641
of 3,119 outputs
Outputs of similar age
#19,620
of 94,540 outputs
Outputs of similar age from Archives of Microbiology
#2
of 6 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,119 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 94,540 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.