Effect of physical training on the recovery of acute exercise, among patients with cardiovascular disease.

Marianna García-Saldivia, Hermes Ilarraza-Lomelí, Jonathan Myers, Jorge Lara, Leopoldo Bueno

Physical training programs (PTP) have shown several beneficial effects for patients with cardiovascular disease (CVD), particularly by increasing survival and quality of life. Physiological response during the effort and recovery phases of an exercise testing, is one of the strongest prognostic markers among patients with CVD. A reasonable mechanism that explains those training effects on survival is through the adaptations seen on heart rate recovery (HRR) and oxygen uptake kinetics at the post-exertional phase (RVO2). Compare the HRR and RVO2 values before and after a PTP in patients with CVD. We studied a cohort of patients included in a cardiac rehabilitation program, whom performed a cardiopulmonary exercise testing (CPX). Then, risk stratification and an individualized exercise training program were performed. The exercise training program included 20 sessions of aerobic exercise, 30min a day, five times a week, at moderate intensity. Finally, a second CPX was performed. A total of 215 patients were included. Peak oxygen uptake values rose 2.2±5.2ml/kg/min (p<0.001), HRR increased 1.6±10bpm (p<0.05) and RVO2 improved -21±98s (p<0.001). A post-hoc analysis show that the percentage of maximum heart rate remained statistically associated with HRR increment. Furthermore, diabetes and sedentarism were strongly related to RVO2 improvement. No correlation between HRR and RVO2 was found (R(2)=0.002). Physical exercise was associated with a beneficial effect on HRR and RVO2. Nevertheless, both variables were statistically unrelated.