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Intraoperative “Kounis syndrome” that improved electrocardiography changes and hemodynamic situation after administering nitroglycerine

Overview of attention for article published in Brazilian Journal of Anesthesiology, October 2013
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Title
Intraoperative “Kounis syndrome” that improved electrocardiography changes and hemodynamic situation after administering nitroglycerine
Published in
Brazilian Journal of Anesthesiology, October 2013
DOI 10.1016/j.bjane.2013.06.015
Pubmed ID
Authors

Victoria O. Sánchez, Luisa C. Roca, Angel del P. Moreno

Abstract

A 58-year-old female without cardiovascular risk factors, was going to be operated to repair the rotator cuff. Induction and interscalene brachial plexus block were uneventful, but after her placement for surgery the patient started with severe bronchospasm, hypotension, cutaneous allergic reaction and ST elevation on the electrocardiogram. An anaphylactic shock was suspected and treated but until the perfusion of nitroglycerina was started no electrocardiographic changes resolved. After necessary diagnostic test the final diagnosis was variant I of Kounis syndrome due to cefazolin and rocuronium. Ephinephrine is the cornerstone of treatment for anaphylaxis but should we use it if the anaphylactic reaction is also accompanied by myocardial ischemia? The answer is that we should not use it because myocardial ischemia in this syndrome is caused by vasospasm, so it would be more useful drugs such as nitroglycerin. But what if we do not know if it is a Kounis syndrome or not? In this article we report our experience that maybe could help you in a similar situation.

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The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Other 4 18%
Student > Master 4 18%
Student > Postgraduate 4 18%
Researcher 3 14%
Student > Ph. D. Student 2 9%
Other 2 9%
Unknown 3 14%
Readers by discipline Count As %
Medicine and Dentistry 12 55%
Pharmacology, Toxicology and Pharmaceutical Science 2 9%
Nursing and Health Professions 2 9%
Social Sciences 1 5%
Unknown 5 23%