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Sedation with dexmedetomidine for conducting electroencephalogram in a patient with Angelman syndrome: a case report

Overview of attention for article published in Brazilian Journal of Anesthesiology, March 2014
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Title
Sedation with dexmedetomidine for conducting electroencephalogram in a patient with Angelman syndrome: a case report
Published in
Brazilian Journal of Anesthesiology, March 2014
DOI 10.1016/j.bjane.2013.06.020
Pubmed ID
Authors

Magda Lourenço Fernandes, Maria do Carmo Santos, Renato Santiago Gomez

Abstract

Angelman syndrome is characterized by severe mental retardation and speech and seizure disorders. This rare genetic condition is associated with changes in GABAA receptor. Patients with Angelman syndrome need to be sedated during an electroencephalogram ordered for diagnostic purposes or evolutionary control. Dexmedetomidine, whose action is independent of GABA receptor, promotes a sleep similar to physiological sleep and can facilitate the performing of this examination in patients with Angelman syndrome. Female patient, 14 years old, with Angelman syndrome; electroencephalogram done under sedation with dexmedetomidine. The procedure was uneventful and bradycardia or respiratory depression was not recorded. The examination was successfully interpreted and epileptiform activity was not observed. Dexmedetomidine promoted satisfactory sedation, was well tolerated and enabled the interpretation of the electroencephalogram in a patient with Angelman syndrome and seizure disorder.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 8 22%
Student > Master 8 22%
Student > Bachelor 4 11%
Student > Ph. D. Student 3 8%
Student > Doctoral Student 2 6%
Other 5 14%
Unknown 6 17%
Readers by discipline Count As %
Unspecified 8 22%
Psychology 5 14%
Medicine and Dentistry 5 14%
Neuroscience 4 11%
Nursing and Health Professions 2 6%
Other 7 19%
Unknown 5 14%