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Mendeley readers
| Title |
Age-adjusted international prognostic index is a predictor of survival in gastric diffuse B-cell non-Hodgkin lymphoma patients
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|---|---|
| Published in |
Hematology Transfusion and Cell Therapy, May 2016
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| DOI | 10.1016/j.bjhh.2016.04.010 |
| Pubmed ID | |
| Authors |
Marcia Torresan Delamain, Maria Gomes da Silva, Eliana Cristina Martins Miranda, Joana Desterro, Stefano Luminari, Anna Fedina, Francesco Merli, Carlos Sergio Chiattone, Katia Borgia Barbosa Pagnano, Massimo Federico, Carmino Antonio de Souza |
| Abstract |
The clinical course of gastric lymphoma is heterogeneous and clinical symptoms and some factors have been related to prognosis. The present study aims to identify prognostic factors in gastric diffuse B-cell non-Hodgkin lymphoma diagnosed and treated in different countries. A consecutive series of gastric diffuse B-cell non-Hodgkin lymphoma patients diagnosed and treated in Brazil, Portugal and Italy, between February 2008 and December 2014 was evaluated. Of 104 patients, 57 were female and the median age was 69 years (range: 28-88). The distribution of the age-adjusted international prognostic index was 12/95 (13%) high risk, 20/95 (21%) high-intermediate risk and 63/95 (66%) low/low-intermediate risk. Symptoms included abdominal pain (63/74), weight loss (57/73), dysphagia (37/72) and nausea/vomiting (37/72). Bulky disease was found in 24% of the cases, anemia in 33 of 76 patients and bleeding in 22 of 72 patients. The median follow-up time was 25 months (range: 1-77 months), with 1- and 5-year survival rates of 79% and 76%, respectively. The multivariate Cox Regression identified the age-adjusted international prognostic index as a predictor of death (hazard risk: 3.62; 95% confidence interval: 2.21-5.93; p-value <0.0001). This series identified the age-adjusted international prognostic index as predictive of mortality in patients treated with conventional immunochemotherapy. |
Mendeley readers
The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 27 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 5 | 19% |
| Other | 4 | 15% |
| Professor | 3 | 11% |
| Student > Master | 3 | 11% |
| Researcher | 2 | 7% |
| Other | 6 | 22% |
| Unknown | 4 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 63% |
| Nursing and Health Professions | 2 | 7% |
| Chemistry | 1 | 4% |
| Biochemistry, Genetics and Molecular Biology | 1 | 4% |
| Unknown | 6 | 22% |