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Epidemiology of Clostridium difficile: a hospital-based descriptive study in Argentina and Mexico

Overview of attention for article published in Brazilian Journal of Infectious Diseases, August 2014
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  • Good Attention Score compared to outputs of the same age and source (66th percentile)

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Title
Epidemiology of Clostridium difficile: a hospital-based descriptive study in Argentina and Mexico
Published in
Brazilian Journal of Infectious Diseases, August 2014
DOI 10.1016/j.bjid.2014.07.004
Pubmed ID
Authors

Gustavo Lopardo, Rayo Morfin-Otero, Iliana Isabel Moran-Vazquez, Fernando Noriega, Betzana Zambrano, Christine Luxemburger, Ginamarie Foglia, Enrique Eduardo Rivas

Abstract

A prospective study was conducted in four tertiary hospitals in Argentina and Mexico in order to describe the occurrence of Clostridium difficile infection (CDI) in these settings. The objective was to evaluate the incidence of CDI in at-risk populations in Argentina (one center) and Mexico (three centers) and to further explore potential study sites for vaccine development in this region. A prospective, descriptive, CDI surveillance study was conducted among hospitalized patients aged ≥40 years who had received ≥48h of antibiotic treatment. Stool samples were collected from those with diarrhea within 30 days after starting antibiotics and analyzed for toxins A and B by ELISA, and positive samples were further tested by toxinogenic culture and restriction endonuclease analysis type assay. Overall, 466 patients were enrolled (193 in Argentina and 273 in Mexico) of whom 414 completed the follow-up. Of these, 15/414 (3.6%) experienced CDI episodes occurring on average 18.1 days after admission to hospital and 15.9 days after the end of antibiotics treatment. The incidence rate of CDI was 3.1 (95% CI 1.7-5.2) per 1000 patient-days during hospitalization, and 1.1 (95% CI 0.6-1.8) per 1000 patient-days during the 30-day follow-up period. This study highlighted the need for further evaluation of the burden of CDI in both countries, including the cases occurring after discharge from hospital.

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X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 1%
Unknown 77 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 15%
Student > Master 10 13%
Student > Bachelor 10 13%
Student > Ph. D. Student 9 12%
Other 6 8%
Other 18 23%
Unknown 13 17%
Readers by discipline Count As %
Medicine and Dentistry 19 24%
Immunology and Microbiology 10 13%
Agricultural and Biological Sciences 8 10%
Biochemistry, Genetics and Molecular Biology 4 5%
Environmental Science 3 4%
Other 9 12%
Unknown 25 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 January 2015.
All research outputs
#15,739,529
of 25,373,627 outputs
Outputs from Brazilian Journal of Infectious Diseases
#339
of 809 outputs
Outputs of similar age
#129,227
of 247,842 outputs
Outputs of similar age from Brazilian Journal of Infectious Diseases
#5
of 15 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 809 research outputs from this source. They receive a mean Attention Score of 3.4. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,842 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.