Title |
Activity of ceftaroline and comparators against pathogens isolated from skin and soft tissue infections in Latin America – results of AWARE surveillance 2012
|
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Published in |
Brazilian Journal of Infectious Diseases, October 2015
|
DOI | 10.1016/j.bjid.2015.08.011 |
Pubmed ID | |
Authors |
Daryl Hoban, Douglas Biedenbach, Daniel Sahm, Edina Reiszner, Joseph Iaconis |
Abstract |
As part of the Assessing Worldwide Antimicrobial Resistance Evaluation (AWARE) surveillance program in 2012 the in vitro activity of ceftaroline and relevant comparator antimicrobials was evaluated in six Latin American countries (Argentina, Brazil, Chile, Colombia, Mexico and Venezuela) against pathogens isolated from patients with hospital associated skin and soft tissue infections (SSTIs). The study documented that ceftaroline was highly active (MIC90 0.25mg/L/% susceptible 100%) against methicillin-susceptible Staphylococcus aureus, methicillin-resistant S. aureus (MIC90 2mg/L/% susceptible 83.3%) and β-hemolytic streptococci (MIC90 0.008-0.015mg/L/% susceptible 100%). The activity of ceftaroline against selected species of Enterobacteriaceae was dependent upon the presence or absence of extended-spectrum β-lactamases (ESBLs). Against ESBL screen-negative Escherichia coli, Klebsiella pneumoniae, and Klebsiella oxytoca the MIC90 and percent susceptible for ceftaroline were (0.5mg/L/94.1%), (0.5mg/L/99.0%) and (0.5mg/L/91.5%), respectively. Ceftaroline demonstrated potent activity against a recent collection of pathogens associated with SSTI in six Latin American countries in 2012. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Colombia | 1 | 20% |
United Kingdom | 1 | 20% |
Brazil | 1 | 20% |
Australia | 1 | 20% |
Unknown | 1 | 20% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 57 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 19% |
Student > Master | 8 | 14% |
Student > Bachelor | 6 | 11% |
Student > Ph. D. Student | 6 | 11% |
Professor | 3 | 5% |
Other | 5 | 9% |
Unknown | 18 | 32% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 15 | 26% |
Immunology and Microbiology | 5 | 9% |
Nursing and Health Professions | 4 | 7% |
Agricultural and Biological Sciences | 4 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
Other | 7 | 12% |
Unknown | 19 | 33% |