↓ Skip to main content

Serum levels of neurotrophic factors in active toxoplasmic retinochoroiditis

Overview of attention for article published in Brazilian Journal of Infectious Diseases, December 2016
Altmetric Badge

Mentioned by

facebook
1 Facebook page

Citations

dimensions_citation
4 Dimensions

Readers on

mendeley
25 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Serum levels of neurotrophic factors in active toxoplasmic retinochoroiditis
Published in
Brazilian Journal of Infectious Diseases, December 2016
DOI 10.1016/j.bjid.2016.11.005
Pubmed ID
Authors

Cynthia Azeredo Cordeiro, Erica Leandro Marciano Vieira, Natália Pessoa Rocha, Vinicius Monteiro Castro, Juliana Lambert Oréfice, Tatiana Barichello, Rogerio Alves Costa, Fernando Oréfice, Lucy Young, Antonio Lucio Teixeira

Abstract

Toxoplasmic retinochoroiditis (TR) is the most common identifiable cause of posterior uveitis in Brazil. Response to treatment and clinical presentation may vary significantly. We assessed serum levels of brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), neurotrophin (NT)-3, and NT-4/5 in patients with active TR, before and after TR treatment. Twenty patients with active lesion and 15 healthy controls were enrolled in the study. Serum concentration of neurotrophic factors was determined by enzyme-linked immunosorbent assay. BDNF levels were significantly higher in patients before treatment when compared with controls (p=0.0015). There was no significant difference in pro-BDNF, NGF, GDNF, NT-3, and NT-4/5 levels between TR patients and controls. Treatment did not affect the levels of these factors. BDNF may be released in the context of the active TR inflammatory response.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 25 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 24%
Researcher 5 20%
Student > Ph. D. Student 4 16%
Student > Bachelor 3 12%
Professor 3 12%
Other 2 8%
Unknown 2 8%
Readers by discipline Count As %
Medicine and Dentistry 5 20%
Agricultural and Biological Sciences 4 16%
Immunology and Microbiology 3 12%
Environmental Science 2 8%
Nursing and Health Professions 1 4%
Other 6 24%
Unknown 4 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 December 2016.
All research outputs
#22,759,802
of 25,374,647 outputs
Outputs from Brazilian Journal of Infectious Diseases
#645
of 809 outputs
Outputs of similar age
#356,741
of 416,423 outputs
Outputs of similar age from Brazilian Journal of Infectious Diseases
#13
of 17 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 809 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 416,423 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.