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Antimicrobial activity evaluation and comparison of methods of susceptibility for Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacter spp. isolates

Overview of attention for article published in Brazilian Journal of Microbiology, May 2017
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Title
Antimicrobial activity evaluation and comparison of methods of susceptibility for Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacter spp. isolates
Published in
Brazilian Journal of Microbiology, May 2017
DOI 10.1016/j.bjm.2017.01.008
Pubmed ID
Authors

Daniele Zendrini Rechenchoski, Angélica Marim Lopes Dambrozio, Ana Carolina Polano Vivan, Paulo Alfonso Schuroff, Tatiane das Neves Burgos, Marsileni Pelisson, Marcia Regina Eches Perugini, Eliana Carolina Vespero

Abstract

The production of KPC (Klebsiella pneumoniae carbapenemase) is the major mechanism of resistance to carbapenem agents in enterobacterias. In this context, forty KPC-producing Enterobacter spp. clinical isolates were studied. It was evaluated the activity of antimicrobial agents: polymyxin B, tigecycline, ertapenem, imipenem and meropenem, and was performed a comparison of the methodologies used to determine the susceptibility: broth microdilution, Etest(®) (bioMérieux), Vitek 2(®) automated system (bioMérieux) and disc diffusion. It was calculated the minimum inhibitory concentration (MIC) for each antimicrobial and polymyxin B showed the lowest concentrations for broth microdilution. Errors also were calculated among the techniques, tigecycline and ertapenem were the antibiotics with the largest and the lower number of discrepancies, respectively. Moreover, Vitek 2(®) automated system was the method most similar compared to the broth microdilution. Therefore, is important to evaluate the performance of new methods in comparison to the reference method, broth microdilution.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 91 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 15 16%
Researcher 13 14%
Student > Bachelor 13 14%
Student > Ph. D. Student 9 10%
Student > Doctoral Student 3 3%
Other 9 10%
Unknown 29 32%
Readers by discipline Count As %
Medicine and Dentistry 11 12%
Biochemistry, Genetics and Molecular Biology 10 11%
Pharmacology, Toxicology and Pharmaceutical Science 9 10%
Agricultural and Biological Sciences 8 9%
Immunology and Microbiology 6 7%
Other 15 16%
Unknown 32 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 June 2017.
All research outputs
#20,660,571
of 25,382,440 outputs
Outputs from Brazilian Journal of Microbiology
#887
of 1,377 outputs
Outputs of similar age
#250,323
of 325,190 outputs
Outputs of similar age from Brazilian Journal of Microbiology
#14
of 20 outputs
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