Title |
Genome sequencing of two Bacillus anthracis strains: a virulent strain and a vaccinal strain
|
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Published in |
Brazilian Journal of Microbiology, July 2017
|
DOI | 10.1016/j.bjm.2017.04.007 |
Pubmed ID | |
Authors |
Franciele Maboni Siqueira, Samuel Paulo Cibulski, Fabiana Quoos Mayer, David Driemeier, Saulo Petinatti Pavarini, Agueda Palmira Castagna de Vargas |
Abstract |
Bacillus anthracis strain SPV842_15 was isolated from bovine fetus, while B. anthracis strain Brazilian vaccinal was recovered from a commercial vaccine. We report here the genome sequences of both strains. The SPV842_15 genome is composed of a single circular chromosome with a length of 5,228,664 base pairs, and comprises 5911 coding sequences. In turn, the Brazilian vaccinal genome remains in 201 contigs with 5733 coding sequences. Both genomes have an overall C+G content of 35.4%, and 11 genes encoding the ribosomal RNAs (rRNAs) 5S, 16S and 23S. Only the plasmid pX01 sequence, which carries genes for toxins synthesis, was detected and completely assembled for both strains. These plasmids have a length of 181,684 base pairs and a C+G content of 32.5%. These genomic data generate insights about vaccinal B. anthracis virulence. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 27 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 5 | 19% |
Researcher | 5 | 19% |
Student > Master | 4 | 15% |
Student > Doctoral Student | 2 | 7% |
Professor | 1 | 4% |
Other | 3 | 11% |
Unknown | 7 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 7 | 26% |
Immunology and Microbiology | 5 | 19% |
Veterinary Science and Veterinary Medicine | 3 | 11% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Chemistry | 1 | 4% |
Other | 0 | 0% |
Unknown | 10 | 37% |