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Lactobacillus reuteri DSM 17938 shortens acute infectious diarrhea in a pediatric outpatient setting

Overview of attention for article published in Jornal de Pediatria, May 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

blogs
1 blog
patent
1 patent

Citations

dimensions_citation
53 Dimensions

Readers on

mendeley
118 Mendeley
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Title
Lactobacillus reuteri DSM 17938 shortens acute infectious diarrhea in a pediatric outpatient setting
Published in
Jornal de Pediatria, May 2015
DOI 10.1016/j.jped.2014.10.009
Pubmed ID
Authors

Ener Cagri Dinleyici, Nazan Dalgic, Sirin Guven, Ozge Metin, Olcay Yasa, Zafer Kurugol, Ozden Turel, Gonul Tanir, Ahmet Sami Yazar, Vefik Arica, Mesut Sancar, Adem Karbuz, Makbule Eren, Metehan Ozen, Ates Kara, Yvan Vandenplas

Abstract

Two randomized controlled clinical trials have shown that Lactobacillus (L) reuteri DSM 17938 reduces the duration of diarrhea in children hospitalized due to acute infectious diarrhea. This was the first trial evaluating the efficacy of L. reuteri DSM 17938 in outpatient children with acute infectious diarrhea. This was a multicenter, randomized, single-blinded, case control clinical trial in children with acute watery diarrhea. A total of 64 children who presented at outpatient clinics were enrolled. The probiotic group received 1×10(8)CFU L. reuteri DSM 17938 for five days in addition to oral rehydration solution (ORS) and the second group was treated with ORS only. The primary endpoint was the duration of diarrhea (in hours). The secondary endpoint was the number of children with diarrhea at each day of the five days of intervention. Adverse events were also recorded. The mean duration of diarrhea was significantly reduced in the L. reuteri group compared to the control group (approximately 15h, 60.4±24.5h [95% CI: 51.0-69.7h] vs. 74.3±15.3h [95% CI: 68.7-79.9h], p<0.05). The percentage of children with diarrhea was lower in the L. reuteri group (13/29; 44.8%) after 48h than the control group (27/31; 87%; RR: 0.51; 95% CI: 0.34-0.79, p<0.01). From the 72nd hour of intervention onwards, there was no difference between the two groups in the percentage of children with diarrhea. No adverse effects related to L. reuteri were noted. L. reuteri DSM 17938 is effective, safe, and well-tolerated in outpatient children with acute infectious diarrhea.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 118 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 <1%
Brazil 1 <1%
Unknown 116 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 21 18%
Student > Bachelor 19 16%
Other 11 9%
Researcher 10 8%
Student > Postgraduate 10 8%
Other 22 19%
Unknown 25 21%
Readers by discipline Count As %
Medicine and Dentistry 42 36%
Nursing and Health Professions 9 8%
Agricultural and Biological Sciences 9 8%
Immunology and Microbiology 6 5%
Pharmacology, Toxicology and Pharmaceutical Science 6 5%
Other 16 14%
Unknown 30 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 May 2018.
All research outputs
#2,863,852
of 25,374,647 outputs
Outputs from Jornal de Pediatria
#56
of 896 outputs
Outputs of similar age
#35,806
of 279,890 outputs
Outputs of similar age from Jornal de Pediatria
#1
of 14 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 896 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,890 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.