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Spirometry and volumetric capnography in lung function assessment of obese and normal-weight individuals without asthma

Overview of attention for article published in Jornal de Pediatria, April 2017
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Title
Spirometry and volumetric capnography in lung function assessment of obese and normal-weight individuals without asthma
Published in
Jornal de Pediatria, April 2017
DOI 10.1016/j.jped.2016.10.007
Pubmed ID
Authors

Mariana S. Ferreira, Roberto T. Mendes, Fernando A.L. Marson, Mariana P. Zambon, Maria A.R.G.M. Antonio, Ilma A. Paschoal, Adyléia A.D.C. Toro, Silvana D. Severino, Maria A.G.O. Ribeiro, José D. Ribeiro

Abstract

To analyze and compare lung function of obese and healthy, normal-weight children and adolescents, without asthma, through spirometry and volumetric capnography. Cross-sectional study including 77 subjects (38 obese) aged 5-17 years. All subjects underwent spirometry and volumetric capnography. The evaluations were repeated in obese subjects after the use of a bronchodilator. At the spirometry assessment, obese individuals, when compared with the control group, showed lower values of forced expiratory volume in the first second by forced vital capacity (FEV1/FVC) and expiratory flows at 75% and between 25 and 75% of the FVC (p<0.05). Volumetric capnography showed that obese individuals had a higher volume of produced carbon dioxide and alveolar tidal volume (p<0.05). Additionally, the associations between dead space volume and tidal volume, as well as phase-3 slope normalized by tidal volume, were lower in healthy subjects (p<0.05). These data suggest that obesity does not alter ventilation homogeneity, but flow homogeneity. After subdividing the groups by age, a greater difference in lung function was observed in obese and healthy individuals aged >11 years (p<0.05). Even without the diagnosis of asthma by clinical criteria and without response to bronchodilator use, obese individuals showed lower FEV1/FVC values and forced expiratory flow, indicating the presence of an obstructive process. Volumetric capnography showed that obese individuals had higher alveolar tidal volume, with no alterations in ventilation homogeneity, suggesting flow alterations, without affecting lung volumes.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Other 3 13%
Student > Ph. D. Student 3 13%
Student > Master 3 13%
Student > Bachelor 3 13%
Unspecified 2 8%
Other 4 17%
Unknown 6 25%
Readers by discipline Count As %
Medicine and Dentistry 7 29%
Nursing and Health Professions 4 17%
Unspecified 2 8%
Computer Science 1 4%
Environmental Science 1 4%
Other 2 8%
Unknown 7 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 November 2017.
All research outputs
#16,051,091
of 25,382,440 outputs
Outputs from Jornal de Pediatria
#426
of 896 outputs
Outputs of similar age
#184,360
of 324,249 outputs
Outputs of similar age from Jornal de Pediatria
#3
of 13 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 896 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,249 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.