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Recomendaciones para el uso de everolimus en trasplante renal de novo: falsas creencias, mitos y realidades

Overview of attention for article published in Nefrología, May 2017
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Title
Recomendaciones para el uso de everolimus en trasplante renal de novo: falsas creencias, mitos y realidades
Published in
Nefrología, May 2017
DOI 10.1016/j.nefro.2016.11.007
Pubmed ID
Authors

Julio Pascual, Fritz Diekmann, Constantino Fernández-Rivera, Gonzalo Gómez-Marqués, Alex Gutiérrez-Dalmau, María José Pérez-Sáez, Asunción Sancho-Calabuig, Federico Oppenheimer

Abstract

The immunosuppressive combination most commonly used in de novo kidney transplantation comprises a calcineurin inhibitor (CI), tacrolimus, a mycophenolic acid derivative and steroids. The evidence which underlies this practice is based in the Symphony trial with controlled follow-up of one year, in which no comparator group included the combination CI-mTOR inhibitor. Different high-quality clinical trials support the use of everolimus as a standard immunosuppressive drug associated with reduced exposure of a CI in kidney transplantation. This combination could improve health related outcomes in kidney transplantation recipients. The present recommendations constitute an attempt to summarise the scientific evidence supporting this practice, discuss false beliefs, myths and facts, and offer specific guidelines for safe use, avoiding complications.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 38 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 3 8%
Student > Master 3 8%
Student > Bachelor 3 8%
Other 2 5%
Researcher 2 5%
Other 3 8%
Unknown 22 58%
Readers by discipline Count As %
Medicine and Dentistry 10 26%
Nursing and Health Professions 3 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Environmental Science 1 3%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 0 0%
Unknown 22 58%