Title |
Lethality of cytochalasin B and other compounds isolated from fungus Aspergillus sp. (Trichocomaceae) endophyte of Bauhinia guianensis (Fabaceae)
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Published in |
Revista Argentina de Microbiología, August 2016
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DOI | 10.1016/j.ram.2016.04.002 |
Pubmed ID | |
Authors |
André de O. Feitosa, Amanda Cristina S. Dias, Gisele da C. Ramos, Heriberto R. Bitencourt, José Edson S. Siqueira, Patrícia Santana B. Marinho, Andersson Barison, Fernanda M.M. Ocampos, Andrey Moacir do R. Marinho |
Abstract |
Endophytic fungi are fungi that colonize internal tissues of plants; several biologically active compounds have been isolated from these fungi. There are few studies of compounds isolated from endophytic fungi of Amazon plants. Thus, this study aimed the isolation and structural identification of ergosterol (1), ergosterol peroxide (2), mevalonolactone (3), cytochalasin B (4) and cytochalasin H (5) from Aspergillus sp. EJC 04, an endophytic fungus from Bauhinia guianensis. The cytochalasin B (4) and the diacetate derivative of cytochalasin B (4a) showed high lethality in the brine shrimp assay. This is the first occurrence of cytochalasins in Amazonian endophytic fungi from B. guianensis. |
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Unknown | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 30 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 5 | 17% |
Student > Master | 5 | 17% |
Student > Bachelor | 3 | 10% |
Student > Postgraduate | 2 | 7% |
Professor | 2 | 7% |
Other | 4 | 13% |
Unknown | 9 | 30% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 6 | 20% |
Agricultural and Biological Sciences | 6 | 20% |
Chemistry | 3 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Social Sciences | 1 | 3% |
Other | 3 | 10% |
Unknown | 10 | 33% |