Title |
Impact of Childhood Stress on Psychopathology
|
---|---|
Published in |
Revista Brasileira de Psiquiatria, December 2012
|
DOI | 10.1016/j.rbp.2012.04.009 |
Pubmed ID | |
Authors |
Elisa Brietzke, Márcia Kauer Sant’anna, Andréa Jackowski, Rodrigo Grassi-Oliveira, Joanna Bucker, André Zugman, Rodrigo Barbachan Mansur, Rodrigo Affonseca Bressan |
Abstract |
Advances in our knowledge of mental disorder (MD) genetics have contributed to a better understanding of their pathophysiology. Nonetheless, several questions and doubts persist. Recent studies have focused on environmental influences in the development of MDs, and the advent of neuroscientific methodologies has provided new perspectives. Early life events, such as childhood stress, may affect neurodevelopment through mechanisms such as gene-environment interactions and epigenetic regulation, thus leading to diseases in adulthood. The aim of this paper is to review the evidence regarding the role of the environment, particularly childhood stress, in the pathophysiology of MD. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 25% |
Unknown | 3 | 75% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 1% |
Mexico | 2 | <1% |
Australia | 1 | <1% |
Netherlands | 1 | <1% |
United Kingdom | 1 | <1% |
Unknown | 371 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 61 | 16% |
Student > Bachelor | 55 | 14% |
Student > Master | 54 | 14% |
Researcher | 49 | 13% |
Student > Doctoral Student | 26 | 7% |
Other | 46 | 12% |
Unknown | 89 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 102 | 27% |
Medicine and Dentistry | 67 | 18% |
Neuroscience | 30 | 8% |
Social Sciences | 18 | 5% |
Agricultural and Biological Sciences | 17 | 4% |
Other | 41 | 11% |
Unknown | 105 | 28% |