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Pro-inflammatory Cytokines, Biomarkers, Genetics and the Immune System: A Mechanistic Approach of Depression and Psoriasis

Overview of attention for article published in Revista Colombiana de Psiquiatría (English ed ), April 2017
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Title
Pro-inflammatory Cytokines, Biomarkers, Genetics and the Immune System: A Mechanistic Approach of Depression and Psoriasis
Published in
Revista Colombiana de Psiquiatría (English ed ), April 2017
DOI 10.1016/j.rcp.2017.03.002
Pubmed ID
Authors

Daniyal Aleem, Hassaan Tohid

Abstract

To highlight the inflammatory and immunological mechanisms involved in depression and psoriasis. A comprehensive literature search was performed in various databases, in total 145 studies were selected. Depression and psoriasis have an association. Immune mechanisms -the actions of tumor necrosis factor-α, interleukin 1 (IL-1), IL-2, IL-10, IL-22, IL-17, interferon-γ, IL-1β, prostaglandin E2, C-reactive protein, IL-6, and IL-8 etc.-, and some genetic changes are involved. A possible bidirectional relationship of psoriasis and major depression exists; i.e. the depression leads to psoriasis, and psoriasis leads to depression. We recommend more studies in the future to get a deeper and better understanding about this relationship.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 74 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 11 15%
Student > Master 8 11%
Researcher 6 8%
Student > Ph. D. Student 5 7%
Student > Doctoral Student 4 5%
Other 16 22%
Unknown 24 32%
Readers by discipline Count As %
Medicine and Dentistry 10 14%
Biochemistry, Genetics and Molecular Biology 6 8%
Pharmacology, Toxicology and Pharmaceutical Science 5 7%
Psychology 4 5%
Nursing and Health Professions 3 4%
Other 17 23%
Unknown 29 39%