Title |
Pro-inflammatory Cytokines, Biomarkers, Genetics and the Immune System: A Mechanistic Approach of Depression and Psoriasis
|
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Published in |
Revista Colombiana de Psiquiatría (English ed ), April 2017
|
DOI | 10.1016/j.rcp.2017.03.002 |
Pubmed ID | |
Authors |
Daniyal Aleem, Hassaan Tohid |
Abstract |
To highlight the inflammatory and immunological mechanisms involved in depression and psoriasis. A comprehensive literature search was performed in various databases, in total 145 studies were selected. Depression and psoriasis have an association. Immune mechanisms -the actions of tumor necrosis factor-α, interleukin 1 (IL-1), IL-2, IL-10, IL-22, IL-17, interferon-γ, IL-1β, prostaglandin E2, C-reactive protein, IL-6, and IL-8 etc.-, and some genetic changes are involved. A possible bidirectional relationship of psoriasis and major depression exists; i.e. the depression leads to psoriasis, and psoriasis leads to depression. We recommend more studies in the future to get a deeper and better understanding about this relationship. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 74 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 11 | 15% |
Student > Master | 8 | 11% |
Researcher | 6 | 8% |
Student > Ph. D. Student | 5 | 7% |
Student > Doctoral Student | 4 | 5% |
Other | 16 | 22% |
Unknown | 24 | 32% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 14% |
Biochemistry, Genetics and Molecular Biology | 6 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 7% |
Psychology | 4 | 5% |
Nursing and Health Professions | 3 | 4% |
Other | 17 | 23% |
Unknown | 29 | 39% |