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Baixo peso ao nascer e obesidade: associação causal ou casual?

Overview of attention for article published in Revista Paulista de Pediatria, June 2015
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Title
Baixo peso ao nascer e obesidade: associação causal ou casual?
Published in
Revista Paulista de Pediatria, June 2015
DOI 10.1016/j.rpped.2014.09.007
Pubmed ID
Authors

Adolfo Monteiro Ribeiro, Marília de Carvalho Lima, Pedro Israel Cabral de Lira, Giselia Alves Pontes da Silva

Abstract

To present the conceptual foundations that explain how events occurring during intrauterine life may influence body development, emphasizing the interrelation between low birth weight and risk of obesity throughout life. Google Scholar, Library Scientific Electronic Online (SciELO), EBSCO, Scopus, and PubMed were the databases. "Catch-up growth", "life course health", "disease", "child", "development", "early life", "perinatal programming", "epigenetics", "breastfeeding", "small baby syndrome", "phenotype", "micronutrients", "maternal nutrition", "obesity", and "adolescence" were isolated or associated keywords for locating reviews and epidemiological, intervention and experimental studies published between 1934 and 2014, with complete texts in Portuguese and English. Duplicate articles, editorials and reviews were excluded, as well as approaches of diseases different from obesity. Within 47 selected articles among 538 eligible ones, the thrifty phenotype hypothesis, the epigenetic mechanisms and the development plasticity were identified as fundamental factors to explain the mechanisms involved in health and disease throughout life. They admit the possibility that both cardiometabolic events and obesity originate from intrauterine nutritional deficiency, which, associated with a food supply that is excessive to the metabolic needs of the organism in early life stages, causes endocrine changes. However, there may be phenotypic reprogramming for low birth weight newborns from adequate nutritional supply, thus overcoming a restrictive intrauterine environment. Therefore, catch-up growth may indicate recovery from intrauterine constraint, which is associated with short-term benefits or harms in adulthood. Depending on the nutritional adequacy in the first years of life, developmental plasticity may lead to phenotype reprogramming and reduce the risk of obesity.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 96 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 96 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 19 20%
Student > Ph. D. Student 14 15%
Student > Bachelor 11 11%
Student > Doctoral Student 7 7%
Other 6 6%
Other 12 13%
Unknown 27 28%
Readers by discipline Count As %
Medicine and Dentistry 23 24%
Nursing and Health Professions 21 22%
Engineering 3 3%
Agricultural and Biological Sciences 3 3%
Biochemistry, Genetics and Molecular Biology 2 2%
Other 9 9%
Unknown 35 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 July 2015.
All research outputs
#22,759,452
of 25,374,647 outputs
Outputs from Revista Paulista de Pediatria
#347
of 511 outputs
Outputs of similar age
#238,886
of 279,890 outputs
Outputs of similar age from Revista Paulista de Pediatria
#3
of 5 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 511 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,890 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.