↓ Skip to main content

Associação do gene ADRB2 com sobrepeso e asma em crianças e adolescentes e sua relação com a aptidão física

Overview of attention for article published in Revista Paulista de Pediatria, August 2015
Altmetric Badge

Mentioned by

twitter
2 X users

Citations

dimensions_citation
10 Dimensions

Readers on

mendeley
23 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Associação do gene ADRB2 com sobrepeso e asma em crianças e adolescentes e sua relação com a aptidão física
Published in
Revista Paulista de Pediatria, August 2015
DOI 10.1016/j.rpped.2015.01.012
Pubmed ID
Authors

Neiva Leite, Leilane Lazarotto, Gerusa Eisfeld Milano, Ana Claudia Kapp Titski, Cássio Leandro Mühe Consentino, Fernanda de Mattos, Fabiana Antunes de Andrade, Lupe Furtado‐Alle

Abstract

To investigate the association of Arg16Gly and Gln27Glu polymorphisms of β2-adrenergic receptor gene (ADRB2) with the occurrence of asthma and overweight and the gene's influence on anthropometric, clinic, biochemical and physical fitness variables in children and adolescents. Subjects were evaluated for allelic frequencies of the ADRB2 gene, height, weight, body mass index (BMI), BMI Z-score, waist circumference (WC), pubertal stage, resting heart rate (HRres), blood pressure (BP), total cholesterol (TC), glucose, insulin, high density lipoprotein (HDL-C), low density lipoprotein (LDL-C), triglyceride (TG), Homeostasis Metabolic Assessment (HOMA2-IR), Quantitative Insulin Sensitivity Check Index (QUICKI) and maximal oxygen uptake (VO2max). The participants were divided in four groups: overweight asthmatic (n=39), overweight non-asthmatic (n=115), normal weight asthmatic (n=12), and normal weight non-asthmatic (n=40). Regarding the Gln27Glu polymorphism, higher TC was observed in usual genotype individuals than in genetic variant carriers (p = 0.04). No evidence was found that the evaluated polymorphisms are influencing the physical fitness. The Arg16 allele was found more frequently among the normal weight asthmatic group when compared to the normal weight non-asthmatic group (p=0.02), and the Glu27 allele was more frequently found in the overweight asthmatics group when compared to the normal weight non-asthmatic group (p=0.03). The association of Arg16 allele with the occurrence of asthma and of the Glu27 allele with overweight asthmatic adolescents evidenced the contribution of the ADBR2 gene to the development of obesity and asthma.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 30%
Student > Ph. D. Student 5 22%
Student > Master 3 13%
Student > Doctoral Student 2 9%
Other 2 9%
Other 3 13%
Unknown 1 4%
Readers by discipline Count As %
Sports and Recreations 6 26%
Medicine and Dentistry 6 26%
Agricultural and Biological Sciences 3 13%
Biochemistry, Genetics and Molecular Biology 2 9%
Nursing and Health Professions 2 9%
Other 3 13%
Unknown 1 4%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 January 2016.
All research outputs
#20,656,820
of 25,374,647 outputs
Outputs from Revista Paulista de Pediatria
#274
of 511 outputs
Outputs of similar age
#205,337
of 279,607 outputs
Outputs of similar age from Revista Paulista de Pediatria
#9
of 12 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 511 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,607 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.