Title |
Importance of the association of molecular and immunological diagnosis in immunocompetent patient with Histoplasma capsulatum and Cryptoccocus neoformans infection: a case report
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Published in |
Journal of Venomous Animals and Toxins including Tropical Diseases, August 2014
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DOI | 10.1186/1678-9199-20-36 |
Pubmed ID | |
Authors |
Kátia Cristina Dantas, Roseli Santos de Freitas, Roberta Scholz Pinto Garcia, Marcos Vinícius da Silva, Edna Cleide Mendes Muricy, Valdelene Sayuri Kohara, Adriana Pardini Vicentini |
Abstract |
This case reports an immunocompetent 29-year-old woman with suspected pneumonia, suggestive of fungal infection. Immunoblotting analysis reactivity against Histoplasma capsulatum and Paracoccidioides brasiliensis were observed. Nested-PCR in blood employing species-specific primers was positive for H. capsulatum and Cryptococcus neoformans. The evaluation of paucisymptomatic patients with positive results for H. capsulatum and C. neoformans could be relevant for the prevention as well as the possible evaluation of the reactivated quiescent foci. In conclusion, the associated methodology may have contributed to the monitoring endogenous reactivation of these diseases. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 24 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 4 | 17% |
Researcher | 4 | 17% |
Student > Ph. D. Student | 4 | 17% |
Student > Postgraduate | 3 | 13% |
Student > Master | 3 | 13% |
Other | 3 | 13% |
Unknown | 3 | 13% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 6 | 25% |
Agricultural and Biological Sciences | 4 | 17% |
Biochemistry, Genetics and Molecular Biology | 3 | 13% |
Immunology and Microbiology | 3 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 8% |
Other | 4 | 17% |
Unknown | 2 | 8% |