Title |
Using mesenchymal stem cells as a therapy for bone regeneration and repairing
|
---|---|
Published in |
Biological Research, November 2015
|
DOI | 10.1186/s40659-015-0053-4 |
Pubmed ID | |
Authors |
Jin Shao, Weiwei Zhang, Tieyi Yang |
Abstract |
Bone is a unique tissue which could regenerate completely after injury rather than heal itself with a scar. Compared with other tissues the difference is that, during bone repairing and regeneration, after the inflammatory phase the mesenchymal stem cells (MSCs) are recruited to the injury site and differentiate into either chondroblasts or osteoblasts precursors, leading to bone repairing and regeneration. Besides these two precursors, the MSCs can also differentiate into adipocyte precursors, skeletal muscle precursors and some other mesodermal cells. With this multilineage potentiality, the MSCs are probably used to cure bone injury and other woundings in the near future. Here we will introduce the recent developments in understanding the mechanism of MSCs action in bone regeneration and repairing. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 20% |
France | 1 | 20% |
United States | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 60% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Science communicators (journalists, bloggers, editors) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 2% |
Unknown | 129 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 26 | 20% |
Student > Bachelor | 23 | 18% |
Student > Ph. D. Student | 19 | 15% |
Researcher | 16 | 12% |
Student > Doctoral Student | 8 | 6% |
Other | 21 | 16% |
Unknown | 18 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 30 | 23% |
Medicine and Dentistry | 28 | 21% |
Agricultural and Biological Sciences | 17 | 13% |
Engineering | 10 | 8% |
Materials Science | 7 | 5% |
Other | 16 | 12% |
Unknown | 23 | 18% |