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Antiproliferative action of aqueous extracts of Hymenaea stigonocarpa Mart. (Fabaceae) on the cell cycle of Allium cepa L.

Overview of attention for article published in Anais da Academia Brasileira de Ciências, July 2014
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Title
Antiproliferative action of aqueous extracts of Hymenaea stigonocarpa Mart. (Fabaceae) on the cell cycle of Allium cepa L.
Published in
Anais da Academia Brasileira de Ciências, July 2014
DOI 10.1590/0001-3765201420130163
Pubmed ID
Authors

Lourran P Lacerda, Geiz Malaquias, Ana Paula Peron

Abstract

In this study we evaluated the action of crude aqueous extracts obtained from rhytidome of Hymenaea stigonocarpa (jatobá-do-cerrado) on Allium cepa meristematic root cells in three concentrations: 0.082, 0.164, 0.328g/mL, at exposure times of 24 and 48 h. The slides were prepared by the crushing technique, and cells analyzed throughout the cell cycle, totaling 5000 for each control group and concentration. It was found that all three concentrations, including the lowest which is considered ideal for use, in all exposure times, had significant antiproliferative action on the cell cycle of this test system. For cells under division, we observed a high number of cells in prophase. Therefore, under the conditions studied H. stigonocarpa indicated to be cytotoxic.

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The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 3 18%
Student > Bachelor 3 18%
Student > Master 3 18%
Student > Doctoral Student 2 12%
Student > Ph. D. Student 1 6%
Other 0 0%
Unknown 5 29%
Readers by discipline Count As %
Agricultural and Biological Sciences 3 18%
Biochemistry, Genetics and Molecular Biology 3 18%
Chemistry 2 12%
Chemical Engineering 1 6%
Veterinary Science and Veterinary Medicine 1 6%
Other 2 12%
Unknown 5 29%