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Plasma nitric oxide, endothelin-1, arginase and superoxide dismutase in the plasma and placentae from preeclamptic patients

Overview of attention for article published in Anais da Academia Brasileira de Ciências, May 2015
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Title
Plasma nitric oxide, endothelin-1, arginase and superoxide dismutase in the plasma and placentae from preeclamptic patients
Published in
Anais da Academia Brasileira de Ciências, May 2015
DOI 10.1590/0001-3765201520140069
Pubmed ID
Authors

Fabiana C. Bernardi, Francieli Vuolo, Fabricia Petronilho, Monique Michels, Cristiane Ritter, Felipe Dal-Pizzol

Abstract

The aim of this study was to determine parameters of NO metabolism in plasma and placenta of preeclamptic (PE) patients. It was conducted a case-control study at São José Hospital, Brazil. Thirty-three PE and 33 normotensive pregnant were included in the study. The diagnosis of PE was established in accordance with the definitions of American College of Obstetricians and Gynecologists. Peripheral venous blood and placenta samples were obtained at postpartum period. Plasma NO levels and SOD activity were significantly lower and endothelin-1 levels and arginase activity were significantly higher in PE women when compared to controls. None of the analyzed parameters were different in the placenta between groups. Our findings suggest that parameters associated with NO metabolism are altered only at the systemic level, but not in placenta of PE patients.

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Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 22%
Student > Master 5 14%
Researcher 3 8%
Student > Ph. D. Student 3 8%
Student > Doctoral Student 1 3%
Other 3 8%
Unknown 13 36%
Readers by discipline Count As %
Medicine and Dentistry 8 22%
Biochemistry, Genetics and Molecular Biology 4 11%
Agricultural and Biological Sciences 3 8%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Nursing and Health Professions 2 6%
Other 2 6%
Unknown 15 42%