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Mendeley readers
| Title |
Terpene Esters from Natural Products: Synthesis and Evaluation of Cytotoxic Activity
|
|---|---|
| Published in |
Anais da Academia Brasileira de Ciências, September 2017
|
| DOI | 10.1590/0001-3765201720160780 |
| Pubmed ID | |
| Authors |
Mauricio M Victor, Jorge M David, Maria C K Sakukuma, Letícia V Costa-Lotufo, Andrea F Moura, Ana J Araújo |
| Abstract |
Natural steroids and triterpenes such as b-sitosterol, stigmasterol, lupeol, ursolic and betulinic acids were transformed into its hexanoic and oleic esters, to evaluate the influence of chemical modification towards the cytotoxic activities against tumor cells. The derivatives were evaluated against five tumor cell lines [OVCAR-8 (ovarian carcinoma); SF-295 (glioblastoma); HCT-116 (colon adenocarcinoma); HL-60 (leukemia); and PC-3 (prostate carcinoma)] and the results showed only betulinic acid hexyl ester exhibits cytotoxic potential activity. |
Mendeley readers
The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 36 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 6 | 17% |
| Student > Doctoral Student | 4 | 11% |
| Student > Bachelor | 4 | 11% |
| Student > Master | 4 | 11% |
| Researcher | 3 | 8% |
| Other | 4 | 11% |
| Unknown | 11 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 7 | 19% |
| Medicine and Dentistry | 5 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 11% |
| Biochemistry, Genetics and Molecular Biology | 1 | 3% |
| Agricultural and Biological Sciences | 1 | 3% |
| Other | 4 | 11% |
| Unknown | 14 | 39% |