You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
| Title |
Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils
|
|---|---|
| Published in |
Anais da Academia Brasileira de Ciências, September 2017
|
| DOI | 10.1590/0001-3765201720160908 |
| Pubmed ID | |
| Authors |
Maria E A Pinto, Sthéfane G Araújo, Marcela I Morais, Nívea P Sá, Caroline M Lima, Carlos A Rosa, Ezequias P Siqueira, Susana Johann, Luciana A R S Lima |
| Abstract |
Fatty acid methyl esters (FAMEs) were obtained from vegetable oils of soybean, corn and sunflower. The current study was focused on evaluating the antifungal activity of FAMEs mainly against Paracoccidioides spp., as well as testing the interaction of these compounds with commercial antifungal drugs and also their antioxidant potential. FAMEs presented small IC50 values (1.86-9.42 μg/mL). All three FAMEs tested showed antifungal activity against isolates of Paracoccidioides spp. with MIC values ranging from 15.6-500 µg/mL. Sunflower FAMEs exhibited antifungal activity that extended also to other genera, with an MIC of 15.6 μg/mL against Candida glabrata and C. krusei and 31.2 μg/mL against C. parapsilosis. FAMEs exhibited a synergetic effect with itraconazole. The antifungal activity of the FAMEs against isolates of Paracoccidioides spp. is likely due to the presence of methyl linoleate, the major compound present in all three FAMEs. The results obtained indicate the potential of FAMEs as sources for antifungal and antioxidant activity. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 152 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 152 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 24 | 16% |
| Researcher | 18 | 12% |
| Student > Master | 17 | 11% |
| Student > Bachelor | 12 | 8% |
| Student > Doctoral Student | 7 | 5% |
| Other | 20 | 13% |
| Unknown | 54 | 36% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 25 | 16% |
| Biochemistry, Genetics and Molecular Biology | 19 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 16 | 11% |
| Chemistry | 15 | 10% |
| Environmental Science | 3 | 2% |
| Other | 12 | 8% |
| Unknown | 62 | 41% |