↓ Skip to main content

Wilson’s disease presenting as rapid eye movement sleep behavior disorder: a possible window to early treatment

Overview of attention for article published in Arquivos de Neuro-Psiquiatria, September 2014
Altmetric Badge

Mentioned by

twitter
2 X users

Citations

dimensions_citation
27 Dimensions

Readers on

mendeley
56 Mendeley
citeulike
1 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Wilson’s disease presenting as rapid eye movement sleep behavior disorder: a possible window to early treatment
Published in
Arquivos de Neuro-Psiquiatria, September 2014
DOI 10.1590/0004-282x20140118
Pubmed ID
Authors

Gotthard G. Tribl, Edson Bor-Seng-Shu, Mateus C. Trindade, Leandro T. Lucato, Manoel J. Teixeira, Egberto R. Barbosa

Abstract

Objective To describe characteristics of REM sleep behavior disorder in Wilson's disease. Method Questionnaire-based interviews (patients and relatives), neurological examinations, two-week prospective dream-diary, video-polysomnography, transcranial sonography, MRI. Results Four Wilson's disease cases with REM sleep behavior disorder were described; three had REM sleep behavior disorder as initial symptom. All showed mesencephalic tegmental/tectal sonographic hyperechogenicities and two presented ponto-mesencephalic tegmental MRI hyperintensities. Conclusion This first description of REM sleep behavior disorder in Wilson's disease in literature documents REM sleep behavior disorder as a possible presenting symptom of Wilson's disease and adds further evidence to the parallelism of Parkinson's disease and Wilson's disease in phenotype and brainstem topography, which ought to be further studied. REM sleep behavior disorder has prognostic relevance for neurodegeneration in α-synucleinopathies. In Wilson's disease, usefulness of early diagnosis and treatment are already well established. REM sleep behavior disorder in Wilson's disease offers a possible theoretical model for potential early treatment in this extrapyramidal and brainstem paradigm syndrome, previewing the possibility of neuroprotective treatment for REM sleep behavior disorder in "pre-clinical" Parkinson's disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 56 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 16%
Student > Bachelor 8 14%
Researcher 6 11%
Student > Master 6 11%
Student > Doctoral Student 5 9%
Other 7 13%
Unknown 15 27%
Readers by discipline Count As %
Psychology 9 16%
Neuroscience 9 16%
Medicine and Dentistry 8 14%
Nursing and Health Professions 6 11%
Agricultural and Biological Sciences 3 5%
Other 5 9%
Unknown 16 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 February 2015.
All research outputs
#19,942,887
of 25,371,288 outputs
Outputs from Arquivos de Neuro-Psiquiatria
#955
of 1,369 outputs
Outputs of similar age
#171,387
of 248,664 outputs
Outputs of similar age from Arquivos de Neuro-Psiquiatria
#13
of 18 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,369 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 248,664 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.