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Objective short sleep duration is associated with the activity of the hypothalamic-pituitary-adrenal axis in insomnia

Overview of attention for article published in Arquivos de Neuro-Psiquiatria, June 2015
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Title
Objective short sleep duration is associated with the activity of the hypothalamic-pituitary-adrenal axis in insomnia
Published in
Arquivos de Neuro-Psiquiatria, June 2015
DOI 10.1590/0004-282x20150053
Pubmed ID
Authors

Carolina D'Aurea, Dalva Poyares, Ronaldo D Piovezan, Gisele Passos, Sergio Tufik, Marco Tulio de Mello

Abstract

Objective To evaluate the association between objective short sleep duration in patients with insomnia and changes in blood parameters related to hypothalamic-pituitary-adrenal (HPA) axis activity.Method A cross-sectional pilot study was conducted in 30 middle-aged adults with chronic insomnia who were divided into 2 groups according to polysomnography (PSG) total sleep time (TST) (TST > 5h and < 5h). All patients underwent subjective analysis of sleep quality, anthropometric measurements, PSG, and determination off asting blood parameters.Results The results revealed lower sleep efficiency and higher sleep latency for those with a TST < 5h. The subjective sleep quality was worse in the TST < 5h. Significantly, higher glucose and cortisol levels were observed with a TST < 5h. Glucose, cortisol and ACTH levels were inversely correlated with the PSG total sleep time.Conclusion Patients with insomnia with objective short sleep duration had HPA-associated endocrine and metabolic imbalances chronically linked to increases in cardiovascular risk observed with this more severe insomnia phenotype.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Turkey 1 2%
Unknown 45 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 15%
Student > Master 6 13%
Student > Doctoral Student 5 11%
Researcher 5 11%
Student > Bachelor 3 7%
Other 4 9%
Unknown 16 35%
Readers by discipline Count As %
Psychology 6 13%
Medicine and Dentistry 5 11%
Neuroscience 3 7%
Nursing and Health Professions 3 7%
Agricultural and Biological Sciences 3 7%
Other 8 17%
Unknown 18 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 June 2015.
All research outputs
#17,286,645
of 25,374,917 outputs
Outputs from Arquivos de Neuro-Psiquiatria
#757
of 1,368 outputs
Outputs of similar age
#168,503
of 281,412 outputs
Outputs of similar age from Arquivos de Neuro-Psiquiatria
#22
of 25 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,368 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 281,412 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.